类器官服务

• 定制开发服务：提供专业的定制开发服务，以满足您的个性化开发需求。
• 多平台化支持：多种分化技术平台，可支持不同的类器官分化。
• 合规的供应链：拥有符合法规要求的iPSCs来源，安全可靠。
• 全面检测验证：多种方法验证细胞
• /组织特征和功能，确保研究结果和数据分析的准确性。
• 专业的服务团队：为您提供专业的支持与协助。

 

• 类似心脏的形态和律动

The cardiac organoids differentiated using the Human iPSC-Derived Cardiac Organoid Differentiation Kit (Ca. No. RIPO-HWM002K) show regular beating from day 7-13 of differentiation.

• 类似心脏的电生理活动

The electrical activity of the cardiac organoids differentiated using the Human iPSC-Derived Cardiac Organoid Differentiation Kit (Ca. No. RIPO-HWM002K) was recorded using silicon probes (Ca. No. P64-7), revealing electrophysiological activity that closely resembles that of the actual human heart.

大脑类器官验证数据

• 大脑类器官的RNA-Seq分析揭示多神经元和神经胶质细胞标志物的表达

RNA-Seq analysis of cerebral organoid of day 13, day 44 and day 100, showing the expression of many markers for glutamatergic, dopaminergic, cholinergic, serotonergic and GABAergic neuron. In addition, glia cell markers were also expressed.

• 多种电生理手段验证大脑类器官的自发放电神经元活动

A: patch-clamp recording of excitatory neurons sectioned from cerebral organoids at day 102. Excitatory neuron showed stable response to step injection currents. 

B: Recording of cerebral organoid (day 60) using silicon probe. Neurons showed spontaneous activities and different waveforms. 

C: MEA recording indicated spontaneous bursting activities for cerebral organoid (day 86).