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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Mouse C5a anaphylatoxin chemotactic receptor (C5ar1), partial, Biotinylated
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
20μg
英文名称:
Recombinant Mouse C5a anaphylatoxin chemotactic receptor (C5ar1), partial, Biotinylated品名简称:
Recombinant Mouse C5ar1 protein, partial, Biotinylated货号:
CSB-EP003996MO1-B规格:
20μg价格:
1848LC-MS/Western Blot:
/SDS-PAGE:
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.纯度:
Greater than 95% as determined by SDS-PAGE.内毒素:
Not test生物活性:
/基因名:
C5ar1Uniprot No.:
P30993别名:
C5a anaphylatoxin chemotactic receptor;C5a-R;C5aR;CD antigen CD88种属:
Mus musculus (Mouse)蛋白长度:
Partial来源:
E.coli分子量:
52.8 kDa表达区域:
306-351aa氨基酸序列:
QGFHGRLLRSLPSIIRNALSEDSVGRDSKTFTPSTTDTSTRKSQAV蛋白标签:
N-terminal MBP-tagged and C-terminal 6xHis-Avi-tagged产品提供形式:
Liquid or Lyophilized powder缓冲液:
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
3-7 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.功能2:
/文献:
/研究领域:
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文献和实验CD88 分子 CD88 常用单克隆抗体或代号: S5/1,W17/1;(C5aR) 主要表达细胞: My [M] 分子质量(kDa)和结构: gp40 功 能: 补体C5a受体,刺激脱颗粒 CD88 Summary: receptor for C5a, the chemotactic and inflammatory peptide anaphylatoxin
。表达TCRαβ或TCRγδ的小鼠和人T细胞在受到抗CD3-TCR抗体、PHA或抗Fas单抗的诱导时发生凋谢。 (1)活化状态的外周T细胞更易发生凋谢:经丝裂原活化和体外扩增培养的人外周T细胞对凋谢更为敏感。小鼠脾脏T细胞在对凋谢易感之前也需要受到抗原的激活。在活化的T细胞中,对凋谢的敏感性在CD4+和CD8+T细胞亚群之间无差异,在小鼠CD4+细胞中,Th1和Th2亚群之间亦无明显的区别。 (2)细胞因子在凋谢中的作用:目前关于细胞因子在体外诱导和阻止凋谢中发挥作用的报道不尽一致
细胞扩增。在脂肪肝和纤维化合并再生障碍的小鼠模型中,过表达IFRD1可恢复肝细胞增殖能力,提示其有望成为慢性肝病再生障碍的重要干预靶点。该研究揭示了肝细胞代谢调控免疫微环境促进再生的新机制,为再生障碍性肝病治疗提供了新策略。 推荐产品 靶点 重组蛋白 货号 AIM2 Recombinant Human Interferon-inducible protein AIM2 (AIM2), Biotinylated CSB-EP001499HU-B ICAM
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