- 询价
- KA&M BIO
- MAB5129
- 2025年10月11日
- ELISA
- Human
- Bovine viral diarrhea virus (isolate NADL) (BVDV) (Mucosal disease virus)
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- 亚型：
VHH-hFc
- 形态：
Liquid
- 保存条件：
at-20℃
- 适应物种：
Bovine viral diarrhea virus (isolate NADL) (BVDV) (Mucosal disease virus)
- 库存：
99
- 宿主：
Human
- 应用范围：
ELISA
- 浓度：
见说明
- 抗体英文名：
Anti-BVDV Envelope glycoprotein E2 Monoclonal antibody (SAA2088)
- 规格：
50-100ug
抗BVDV Envelope glycoprotein E2单克隆抗体(克隆号SAA2088)上海圻明生物优势供应欢迎咨询。配对抗体小课堂：
Paired antibodies are two antibodies that can bind to an antigenic molecule at the same time. Specifically:
Paired antibodies are commonly used in sandwich ELISA experiments
An antigenic molecule usually has multiple epitopes, and different antibodies can target different epitopes
When two antibodies are able to bind to different epitopes of the same antigenic molecule at the same time, the two antibodies are called paired antibodies
However, not all antibodies against different epitopes can be paired antibodies. Sometimes, when an antibody binds to an antigen, it may cause the configuration of other binding sites to change, making it impossible for other antibodies to bind properly
Steric hindrance effects may also result in two antibodies with close binding sites not being able to bind to the antigen at the same time
Therefore, the preparation of paired antibodies usually requires two steps: first the antibody is prepared, and then the paired antibody is screened
Screening of paired antibodies is typically performed using a sandwich ELISA method of bispecific antibodies, in which different combinations of antibodies are tested to determine which antibodies can be successfully paired
Paired antibodies have important applications in immunology research and diagnostics, especially in assays that require high specificity and sensitivity.
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文献和实验密切相关。七十年代，研究人员用凝胶梯度电泳等 生物 化学方法发现了几十种血小板表面膜蛋白，其中一组被称为糖蛋白I（glycoprotein I, GPⅠ）复合物的膜蛋白与血小板“粘附”功能有关。这组复合物又可分为GPⅠb-Ⅸ复合物和GPⅠa-Ⅱa 复合物两类。1979年，笔者赴法进修血液学，有机会通过杂交瘤技术，鉴定出国际上第一个抗血小板膜糖蛋白I的单克隆抗体（AN51）。这株单克隆抗体（以下简称“单抗” ），与正常血小板特异性结合后，血小板就不能通过vW因子“粘附”到破损
类细胞为效应细胞来构建双特异抗体更为常见：第一.T细胞群中存在着免疫记忆细胞；第二.有证据表明在恶性肿瘤患者体内存在着肿瘤特异性的T细胞；第三.体内外实验表明抗CD3抗体激活的杀伤细胞（CD3AK）比IL-2激活的杀伤细胞（LAK）具有更强大的细胞毒效应[2]。体内外生物学实验结果表明：Diabody能同时与T细胞和癌细胞结合，并通过激活T细胞，来靶向杀灭癌细胞[3，4]。HIT3a[5]和PHMA02[6]是我所研制的鼠源性抗CD3和抗Pgp（P-glycoprotein）单克隆抗体，我们在克隆单克隆抗体
Cloning, Expression, and Functional Analysis of Patient-Derived Hepatitis C Virus Glycoproteins
in the envelope glycoproteins E1 and E2. Knowledge of genotypic and quasispecies variation on viral glycoprotein properties is important in understanding the structure-function relationship of the proteins. Through their perceived role as components of the virion
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