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- 文献和实验
- 技术资料
- 保存条件:
-20℃/-80℃
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Human CAD protein (CAD), partial
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
1mg/100ug/20ug
| 规格: | 1mg | 产品价格: | ¥13860.0 |
|---|---|---|---|
| 规格: | 100ug | 产品价格: | ¥3096.0 |
| 规格: | 20ug | 产品价格: | ¥1656.0 |
Research Areas
OthersUniprot ID
P27708Gene Names
CADAlternative Name(s)
/Lead Time
25-35 business daysOrganism
Homo sapiens (Human)Source
YeastExpression Region
1456-1846aaProtein Length
PartialTag Info
C-terminal 6xHis-taggedTarget Protein Sequence
MTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGITMVCAMPNTRPPIIDAPALALAQKLAEAGARCDFALFLGASSENAGTLGTVAGSAAGLKLYLNETFSELRLDSVVQWMEHFETWPSHLPIVAHAEQQTVAAVLMVAQLTQRSVHICHVARKEEILLIKAAKARGLPVTCEVAPHHLFLSHDDLERLGPGKGEVRPELGSRQDVEALWENMAVIDCFASDHAPHTLEEKCGSRPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIFHLPPQEDTYVEVDLEHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLVPPGYGQDVRKWPQGAVPQLPPSAPATSEMTTTPERPRRGIPGLPDMW
43.5 kDaPurity
Greater than 95% as determined by SDS-PAGE.Endotoxin
/Biological_Activity
/Form
Liquid or Lyophilized powderBuffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.Relevance
This protein is a 'fusion' protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase).Function
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文献和实验式途径是通过TNF受体家族(如CD95)的受体与配体结合开始的。这些配体有癌症坏死因子(TNF),和其他细胞因子,后者可以由如T淋巴细胞分泌。 在FADD(Fas偶联死亡区域蛋白Fas-associated death domain protein)的协助下,受体不断在细胞质中收集半胱天冬酶原8(Procaspase 8)。后者通过高密度自催化激活自身。活化的半胱天冬酶8(Caspase 8)将会引发所谓的Caspase级联反应。因此在艾滋病人体内,很多未受感染的白血球也会凋亡:HIV
human E-cadherin-IgG Fc domain fusion protein (E-cad-Fc) has recently been shown to be extremely efficient in facilitating the culture of human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells under completely defined conditions
siRNA导致小鼠中胆固醇水平降低到与apoB基因敲除小鼠的水平一样低。这种方法能够将许多器官中的apoB蛋白表达水平降低50%。研究人员认为他们的这种胆固醇-siRNA传递系统的原理能够用于指导siRNA沉默一些致病基因。这项研究证明注射的siRNA能够用于疾病治疗,但是目前还要其他一些问题需要解决。 Nature 432, 173 - 178 (11 November 2004); doi:10.1038/nature03121 Therapeutic silencing
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