Stat2 rabbit pAb产品图

Stat2 rabbit pAb

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  • ¥900
  • AAB
  • 上海
  • A21990
  • 2026年04月30日
  • WB,IHC-p,ELISA
  • Rabbit
  • Human,Mouse,Rat
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原:

      Synthesized peptide derived from Stat2 . at AA range: 570-650

    • 形态:

      Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

    • 保存条件:

      -20°C/1 year

    • 克隆性:

      Polyclonal

    • 适应物种:

      Human,Mouse,Rat

    • 保质期:

      1年

    • 宿主:

      Rabbit

    • 应用范围:

      WB,IHC-p,ELISA

    • 浓度:

      1 mg/ml

    • 靶点:

      STAT2

    • 抗体英文名:

      Stat2 rabbit pAb

    • 抗体名:

      Signal transducer and activator of transcription 2

    • 规格:

      50ul

    signal transducer and activator of transcription 2(STAT2) Homo sapiens The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],

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    图标文献和实验
    相关实验
    • Immunochemical Detection of a Fluorophore Derived from the Lipid Peroxidation Product 4-Hydroxy-2-Nonenal and Lysine

      = NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific

    • 丙酮酰化领衔!半年4种代谢物PTM新修饰:顶刊连发全拆解

      :赖氨酸丙酮酰化示意图 4月,电子科技大学医学院郑慧团队在《Cell》首次报道了丙酮酰化,聚焦丙酮酸介导的免疫信号调控机制。 研究证实,糖酵解终产物丙酮酸可共价修饰免疫关键蛋白STAT1的K201位点,该位点处于STAT1‑STAT2蛋白互作界面,发生丙酮酰化后会产生空间位阻,直接阻断异二聚体的组装,进而抑制I型干扰素(IFN‑I)信号通路,下调干扰素刺激基因ISG的表达,削弱机体抗病毒免疫能力。 定量检测显示,细胞葡萄糖浓度升高时,伴随糖酵解通路激活,STAT1‑K201位点丙酮酰化修饰占比可由约

    • 亲和层析凝胶指南

      GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin

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