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SMC1 (phospho Ser957) rabbit p

Ab
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  • ¥900
  • AAB
  • 上海
  • A21661
  • 2025年07月10日
  • WB,IHC-p,ELISA
  • Rabbit
  • Human,Mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      The antiserum was produced against synthesized peptide derived from human SMC1 around the phosphorylation site of Ser957. AA range:931-980

    • 形态

      Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

    • 保存条件

      -20°C/1 year

    • 克隆性

      Polyclonal

    • 适应物种

      Human,Mouse

    • 保质期

      1年

    • 宿主

      Rabbit

    • 应用范围

      WB,IHC-p,ELISA

    • 浓度

      1 mg/ml

    • 靶点

      SMC1A

    • 抗体英文名

      SMC1 (phospho Ser957) rabbit pAb

    • 抗体名

      Structural maintenance of chromosomes protein 1A

    • 规格

      50ul

    structural maintenance of chromosomes 1A(SMC1A) Homo sapiens Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome. Altern

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