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SH21A rabbit pAb

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  • ¥900
  • AAB
  • 上海
  • A21466
  • 2025年07月13日
  • WB,ELISA
  • Rabbit
  • Human,Mouse,Rat
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Synthesized peptide derived from part region of human protein

    • 形态

      Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

    • 保存条件

      -20°C/1 year

    • 克隆性

      Polyclonal

    • 适应物种

      Human,Mouse,Rat

    • 保质期

      1年

    • 宿主

      Rabbit

    • 应用范围

      WB,ELISA

    • 浓度

      1 mg/ml

    • 靶点

      SH2D1A DSHP SAP

    • 抗体英文名

      SH21A rabbit pAb

    • 抗体名

      SH2 domain-containing protein 1A (Duncan disease SH2-protein) (Signaling lymphocytic activation molecule-associated protein) (SLAM-associated protein) (T-cell signal transduction molecule SAP)

    • 规格

      50ul

    SH2 domain containing 1A(SH2D1A) Homo sapiens This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been f

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    图标文献和实验
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