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- 详细信息
- 技术资料
- 免疫原:
Synthetic Peptide of MLKL
- 形态:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 保存条件:
-20°C/1 year
- 克隆性:
Monoclonal
- 适应物种:
Human
- 保质期:
1年
- 宿主:
Mouse
- 应用范围:
IHC-p
- 浓度:
1 mg/ml
- 靶点:
MLKL
- 抗体英文名:
MLKL mouse mAb(8H7)
- 抗体名:
MLKL
- 规格:
50ul
mixed lineage kinase domain like(MLKL) Homo sapiens This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2015],
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MLKL mouse mAb(8H7)
¥900







