IL-4Rα (phospho Tyr497) rabbit pAb

IL-4Rα (phospho Tyr497) rabbit

pAb
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  • ¥900
  • AAB
  • 上海
  • A16249
  • 2025年08月01日
  • WB,IHC-p,IF,ELISA
  • Rabbit
  • Human,Mouse
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    • 详细信息
    • 技术资料
    • 免疫原

      The antiserum was produced against synthesized peptide derived from human IL-4R/CD124 around the phosphorylation site of Tyr497. AA range:463-512

    • 形态

      Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

    • 保存条件

      -20°C/1 year

    • 克隆性

      Polyclonal

    • 适应物种

      Human,Mouse

    • 保质期

      1年

    • 宿主

      Rabbit

    • 应用范围

      WB,IHC-p,IF,ELISA

    • 浓度

      1 mg/ml

    • 靶点

      IL4R

    • 抗体英文名

      IL-4Rα (phospho Tyr497) rabbit pAb

    • 抗体名

      Interleukin-4 receptor subunit alpha

    • 规格

      50ul

    interleukin 4 receptor(IL4R) Homo sapiens This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012],

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