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文献和实验Conjugation of Antibodies to Fluorescein or Rhodamine
The isothiocyanate derivative of the fluorophore, fluorescein or rhodamine, is coupled to the amino groups of IgG antibody in a one-step procedure and excess label is removed by gel filtration.
Polysaccharicb-Conjugate Vaccines
It was recognized early this century that small molecules, called haptens, can be made immunogenic after conjugation to carrier proteins (1 ), This principle was thereafter applied successfully to improve the rmmunogenicity of (poly
AntibodyDrug Conjugate Payloads
Toxin payloads, or drugs, are the crucial components of therapeutic antibody–drug conjugates (ADCs). This review will give an introduction on the requirements that make a toxic compound suitable to be used in an antitumoral ADC
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