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- Profoldin
- PARP-1000
- 2025年07月15日
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1000 assays
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文献和实验Activity Assays for Poly-ADP Ribose Polymerase
Poly(ADP-ribose) polymerase (PARP-1) is a nuclear enzyme that has traditionally been thought to require discontinuous or “damaged” DNA (dcDNA) as a coenzyme, a preconception that has limited research mainly to its role in cell pathology, i.e
Poly (ADP-ribosyl)ation of proteins is a posttranslational modification mediated by poly (ADP-ribose) polymerases (PARPs) that uses NAD+ as substrate to form the negatively charged polymer of poly (ADP-ribose) (PAR). After DNA damage, PARP
A general method to express and purify full-length human poly(ADP-ribose) polymerase-1 (PARP-1), individual PARP-1 domains, and groups of PARP-1 domains from Escherichia coli cells is described. The procedure allows for robust production
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