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文献和实验) and zinc finger (Zn) domains, and splice sites. The cap ORF produces three proteins, and the starts sites (VP1, VP2, and VP3) are indicted by right-angled arrows. Regions proposed to be on the exterior of the AAV2 capsid based on homology with canine
Generation of Recombinant Adeno-Associated Virus
open reading frame (ORF) encodes four Rep proteins, Rep78, Rep68, Rep52, and Rep40. The right ORF encodes three Cap proteins, VP1, VP2, and VP3.
The JC Virus-Like Particle Overlay Assay
, and a virus-like particle (VLP) consisting of recombinant VP1 made from Escherichia coli exhibit a virion-like structure and physiological functions (cellular attachment and intracytoplasmic trafficking) similar to those of JCV virions. To examine
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