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文献和实验Human T-cell leukemia virus type 2 (HTLV-2) was first isolated from leukemia patients, but has been found to be endemic among asymptomatic groups worldwide, including certain American Indian tribes (1 ). The virus infection is associated
The transfer of homozygous C57Bl/6 (B6) or DBA/2 (DBA) parental strain T cells into normal B6D2F1 mice in the parent-into-F1 (p → F1) model results in a graft-vs.-host disease (GVHD) that takes one of the following two forms: (a) acute GVHD
Retroviral Transfer of T-Cell Receptor Genes into Human Peripheral Blood Lymphocytes
We are developing strategies to target tumor-associated antigens (TAA) and viral antigens by genetically modifying patient peripheral blood lymphocytes to produce antitumor or antiviral reactive cytotoxic T-lymphocyte (CTL). To this end
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