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文献和实验Gene Editing in One‐Cell Embryos by Zinc‐Finger and TAL Nucleases
editing using sequence‐specific nucleases. Sequence‐specific nucleases are composed of a domain that binds to the target gene via zinc‐finger or TAL effector‐based DNA recognition motifs. The DNA binding part is fused to the nonspecific nuclease domain
【求助】请问CDGSH锌指结构域中的“CDGSH”是指什么？
zjhua 请问CDGSH锌指结构域中的“CDGSH”是指什么？ lalala_2004 Iron-binding zinc finger CDGSH type The CDGSH-type zinc finger domain binds iron rather than zinc as a redox-active pH-labile 2Fe-2S cluster. The conserved sequence C
) and zinc finger (Zn) domains, and splice sites. The cap ORF produces three proteins, and the starts sites (VP1, VP2, and VP3) are indicted by right-angled arrows. Regions proposed to be on the exterior of the AAV2 capsid based on homology with canine
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