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文献和实验The airways are continuously challenged by a variety of stimuli including bacteria, viruses, allergens, and inflammatory factors that act as agonists for G protein-coupled receptors (GPCR). Intracellular calcium (Ca2+ i ) mobilization
associates with the recognition protein C1q. The C1 complex circulates in serum as a zymogen and is activated upon binding of C1q to appropriate targets, such as antigen–antibody complexes. This property is used for the purification of C1r and C1s from human
Characterization of Calcium Channel Binding
, A., Klockner, U., Schneider, T., and Perez‐Reyes, E. 1999. Cloning and expression of a novel member of the low voltage‐activated T‐type calcium channel family. J. Neurosci. 19:1912‐21
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