Recombinant Human Xeroderma Pi

Nucleotide Excision Repair Assay in Drosophila melanogaster Using Established Cell Lines

by genetic analyses of mainly human, rodent, and yeast repairdeficient mutants (1 ,2 ). In particular, cultured cells derived from patients with xeroderma pigmentosum (XP), a human autosomal-recessive disease causing defects in NER, as well as from rodent

Nonisotopic In Situ Hybridization for the Detection of Nuclear Retinoid Receptor Transcripts in Tissue Sections

and neck area and the skin in xeroderma pigmentosum patients (4 –9 ). They are also useful in the therapy of several types of human cancer, primarily acute promyelocytic leukemia (9 –13 ). It is thought that the ability of retinoids to modulate gene

Polymorphisms of DNA Repair Genes: ADPRT, XRCC1, and XPD and Cancer Risk in Genetic Epidemiology

Many studies have suggested that adenosine diphosphate ribosyl transferase (ADPRT), X-ray repair cross-complementing 1 (XRCC1), and xeroderma pigmentosum complementary group D (XPD) are three major DNA base excision repair (BER) genes