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文献和实验Functional Studies of Dual-Specificity Phosphatases
which are specific for phosphotyrosine, dual-specificity enzymes can dephosphorylate both phosphotyrosme and phosphoserine/phosphothreonine. All tyrosine phosphatases, including dual-specificity enzymes, are characterized by a conserved-sequence motif HCXXGXXRS/T
Dual- and Triple-Color Fluorospot
实验原理 ELISPOT has, due to its high sensitivity and simplicity, proven valuable for assessing antigen-specific T-cell responses, both with regard to specificity and magnitude. One limitation of the regular ELISPOT method
Discovery of Protein Kinase Phosphatase Inhibitors
with chemical biology and high-content multiparametric analyses and was developed as a screening approach to discover protein phosphatase inhibitors. Using a dual specificity mitogen-activated protein kinase phosphatase as an example, a detailed protocol
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