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文献和实验第97期靶点速递:GPNMB连登Cell+Nat Cancer,10个新靶点抢先看
10 靶点:P2RY2 应用:治疗实体瘤免疫治疗耐药的潜在靶点 来源:Extracellular ATP–P2RY2 signaling drives intratumoral prostaglandin E2 accumulation and adaptive resistance to immunotherapy in solid tumors.Immunity, 2026 Jul 14 文献内容 德国癌症研究中心孙
Measurement of Mitochondrial DNA Copy Number
dependent on a number of nuclear proteins. Defects in these nuclear genes can lead to mitochondrial DNA (mtDNA) depletion (Spinazzola et al. Biosci Rep 27:39–51, 2007). The mitochondrial DNA (mtDNA) depletion syndromes (MDDSs) are autosomal recessive
Gene Editing in One‐Cell Embryos by Zinc‐Finger and TAL Nucleases
immunoglobulin gene disruption and targeted replacement in rabbit using zinc finger nucleases. PLoS One 6:e21045. Gallagher, S. R. 2011. Quantitation of DNA and RNA with absorption
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