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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
Aurora Kinases-IN-2
- 库存:
10
- 供应商:
TargetMol
- CAS号:
2241914-86-1
- 规格:
100 mg/50 mg/25 mg
| 规格: | 100 mg | 产品价格: | ¥17500.0 |
|---|---|---|---|
| 规格: | 50 mg | 产品价格: | ¥13800.0 |
| 规格: | 25 mg | 产品价格: | ¥10600.0 |
Product Introduction
Bioactivity
英文名:Aurora Kinases-IN-2
描述:Aurora Kinases-IN-2 (compound 12Aj) is a potent inhibitor of Aurora kinases, acting on Aurora A (IC50: 90 nM) and Aurora B (IC50: 152 nM). Aurora Kinases-IN-2 can be used in cancer research.

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文献和实验A method for analyzing the ubiquitination and degradation of aurora-A
many other regulatory proteins. Aurora kinases are involved in mitotic spindle formation as well as in cytokinesis. The abundance and activity of the kinase is precisely regulated during the cell cycle. To understand how proteolysis regulates transitions
Studying the Roles of Aurora-C Kinase During Meiosis in Mouse Oocytes
We previously isolated Aurora-C (Aurkc/Aie1 ) in a screen for kinases expressed in mouse sperm and eggs. Aurora-C kinase was reported to be a chromosomal passenger protein that plays critical roles in chromosome alignment
The Ipl1/Aurora Kinase Family: Methods of Inhibition and Functional Analysis in Mammalian Cells
The Ipl1/Aurora family of protein kinases are required for accurate chromosome segregation. Because members of this family are often overexpressed in human tumors, they have recently received much attention, both from the academic community
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