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P00092 Recombinant Human TREM-1 细胞因子/蛋白
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￥1092P00218 Recombinant Human C-C Motif Chemokine 2/CCL2/MCP-1 细胞因子/蛋白
￥1560P00268 N Protein (E.coli，N-6His) 细胞因子/蛋白
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￥988
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- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
500ug/10ug/50ug/1mg
| 规格： | 500ug | 产品价格： | ￥6048.0 |
|---|---|---|---|
| 规格： | 10ug | 产品价格： | ￥624.0 |
| 规格： | 50ug | 产品价格： | ￥1248.0 |
| 规格： | 1mg | 产品价格： | ￥8640.0 |
Recombinant Human Tumor Necrosis Factor alpha is produced by our E.coli expression system and the target gene encoding Val77-Leu233 is expressed.
备注：产品信息可能会有优化升级。请以实际标签信息为准。
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Loss-of-function mutations in Keratin 32 gene disrupt skin immune homeostasis in pityriasis rubra pilaris
成员:Shi Peidian, Chen Wenjie, Lyu Xinxing, Wang Zhenzhen, Li Wenchao, Jia Fengming, Zheng Chunzhi, Liu Tingting, Wang Chuan, Zhang Yuan, Mi Zihao, Sun Yonghu, Chen Xuechao, Chen Shengli, Zhou Guizhi, Liu Yongxia, Lin Yingjie, Bai Fuxiang, Sun Qing, Ogese Mond
论文因子:14.7 发表期刊:Nature Communications pmid:39048559
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Triptolide mitigates the inhibition of osteogenesis induced by TNF-α in human periodontal ligament stem cells via the p-IκBα/NF-κB signaling pathway: an in-vitro study
成员:Chen Hao, Zhang Lina, Du Simeng, Yang Daiwei, Cui Xiaobin, Zhao Huadong, Zhang Jun
论文因子:3.9 发表期刊:BMC Complementary Medicine and Therapies pmid:38448925
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Topological insulator Bi2Se3 based electrochemical aptasensors for the application of sensitive detection of interferon-γ
成员:Yetong Wu, Peng Zhu, Yujiu Jiang, Xu Zhang, Zhiwei Wang, Bingteng Xie, Tinglu Song, Fulai Zhang, Aiqin Luo, Shanshan Li, Xiaolu Xiong, Junfeng Han
论文因子:7.571 发表期刊:Journal of Materials Chemistry B pmid:36537727
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:MicroRNA-181a-5p alleviates acute liver failure in mice by inhibiting HMGB1
成员:Qianwen Zhang, Yiyu He, Hao Xu, Yuqiao Zeng, Li Wang, Zengxi Xue, Qingyun Sun, Likun Wang
论文因子:1.6 发表期刊:CELLULAR AND MOLECULAR BIOLOGY pmid:37807324
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Nuclear translocation of PKM2 mediates keratinocyte metabolic reprogramming in psoriasis
成员:Luting Yang, Jie Zhang, Chunqing Hu, Xiaowen Chen, Yang Yang, Huihao Tang, Xiaolei Ding, Yaping Yan
论文因子:3.6 发表期刊:EXPERIMENTAL DERMATOLOGY pmid:37688280
| 基本信息 | |
| 基因名 | |
| 别名 | Tumor Necrosis Factor;Cachectin;TNF-Alpha;Tumor Necrosis Factor Ligand Superfamily Member2;TNF-a;TNF;TNFA;TNFSF2 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0. |
| 溶解性 | Solube in water |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 区间范围 | MVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISR IAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL |
| 背景说明 | TNFα is a homotrimer with a subunit molecular mass of 17 kD cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR.It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines.It plays a major role in growth regulation，differentiation，inflammation，viral replication，tumorigenesis，autoimmune diseases and in viral，bacterial，fungal，and parasitic infections.Besides inducing hemorrhagic necrosis of tumors，TNF was found to be involved in tumorigenesis，tumor metastasis，viral replication，septic shock，fever，inflammation，and autoimmune diseases including Crohn’s disease，and rheumatoid arthritis as well as graft-versus-host disease. |
| 来源 | E.coli |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/μg(1 EU/μg)as determined by LAL test. |
| 单位 | 支 |
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文献和实验【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Loss-of-function mutations in Keratin 32 gene disrupt skin immune homeostasis in pityriasis rubra pilaris
成员:Shi Peidian, Chen Wenjie, Lyu Xinxing, Wang Zhenzhen, Li Wenchao, Jia Fengming, Zheng Chunzhi, Liu Tingting, Wang Chuan, Zhang Yuan, Mi Zihao, Sun Yonghu, Chen Xuechao, Chen Shengli, Zhou Guizhi, Liu Yongxia, Lin Yingjie, Bai Fuxiang, Sun Qing, Ogese Mond
论文因子:14.7 发表期刊:Nature Communications pmid:39048559
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Triptolide mitigates the inhibition of osteogenesis induced by TNF-α in human periodontal ligament stem cells via the p-IκBα/NF-κB signaling pathway: an in-vitro study
成员:Chen Hao, Zhang Lina, Du Simeng, Yang Daiwei, Cui Xiaobin, Zhao Huadong, Zhang Jun
论文因子:3.9 发表期刊:BMC Complementary Medicine and Therapies pmid:38448925
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Topological insulator Bi2Se3 based electrochemical aptasensors for the application of sensitive detection of interferon-γ
成员:Yetong Wu, Peng Zhu, Yujiu Jiang, Xu Zhang, Zhiwei Wang, Bingteng Xie, Tinglu Song, Fulai Zhang, Aiqin Luo, Shanshan Li, Xiaolu Xiong, Junfeng Han
论文因子:7.571 发表期刊:Journal of Materials Chemistry B pmid:36537727
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:MicroRNA-181a-5p alleviates acute liver failure in mice by inhibiting HMGB1
成员:Qianwen Zhang, Yiyu He, Hao Xu, Yuqiao Zeng, Li Wang, Zengxi Xue, Qingyun Sun, Likun Wang
论文因子:1.6 发表期刊:CELLULAR AND MOLECULAR BIOLOGY pmid:37807324
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Nuclear translocation of PKM2 mediates keratinocyte metabolic reprogramming in psoriasis
成员:Luting Yang, Jie Zhang, Chunqing Hu, Xiaowen Chen, Yang Yang, Huihao Tang, Xiaolei Ding, Yaping Yan
论文因子:3.6 发表期刊:EXPERIMENTAL DERMATOLOGY pmid:37688280
Secretion of Recombinant Human Insulin-Like Growth Factor I (IGF-I)
The development of efficient recombinant protein production processes can be a critical factor in whether or not a pharmaceutical therapeutic protein can enter human clinical trials and ultimately the marketplace. This is especially true
In this chapter we describe efficient procedures for the construction, expression and screening of comprehensive libraries of human Fab antibody fragments displayed on the surface of filamentous phage. Phagemid vectors are used for placing
我们知道，PeproTech的所有细胞因子和蛋白均为冻干粉，这使得运输非常便捷，只要常温即可。而且，细胞因子和蛋白冻干粉非常稳定，在-20℃或-80℃条件下可保存数年。冻干粉在使用前需进行溶解，然后以液体形式加到培养体系或注射入动物体内。溶解步骤非常关键，因溶解不好会导致细胞因子或蛋白的失活，这也是很多用户在实际使用中经常遇到的问题。 那么，应该如何进行正确的溶解呢？ 下面我们以Recombinant Human IL-4 (重组人IL-4，产品编号：200-04)的说明书为例
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