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- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
500ug/10ug/50ug/1mg
| 规格： | 500ug | 产品价格： | ￥6048.0 |
|---|---|---|---|
| 规格： | 10ug | 产品价格： | ￥624.0 |
| 规格： | 50ug | 产品价格： | ￥1248.0 |
| 规格： | 1mg | 产品价格： | ￥8640.0 |
Recombinant Human Tumor Necrosis Factor alpha is produced by our E.coli expression system and the target gene encoding Val77-Leu233 is expressed.
备注：产品信息可能会有优化升级。请以实际标签信息为准。
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Loss-of-function mutations in Keratin 32 gene disrupt skin immune homeostasis in pityriasis rubra pilaris
成员:Shi Peidian, Chen Wenjie, Lyu Xinxing, Wang Zhenzhen, Li Wenchao, Jia Fengming, Zheng Chunzhi, Liu Tingting, Wang Chuan, Zhang Yuan, Mi Zihao, Sun Yonghu, Chen Xuechao, Chen Shengli, Zhou Guizhi, Liu Yongxia, Lin Yingjie, Bai Fuxiang, Sun Qing, Ogese Mond
论文因子:14.7 发表期刊:Nature Communications pmid:39048559
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Triptolide mitigates the inhibition of osteogenesis induced by TNF-α in human periodontal ligament stem cells via the p-IκBα/NF-κB signaling pathway: an in-vitro study
成员:Chen Hao, Zhang Lina, Du Simeng, Yang Daiwei, Cui Xiaobin, Zhao Huadong, Zhang Jun
论文因子:3.9 发表期刊:BMC Complementary Medicine and Therapies pmid:38448925
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Topological insulator Bi2Se3 based electrochemical aptasensors for the application of sensitive detection of interferon-γ
成员:Yetong Wu, Peng Zhu, Yujiu Jiang, Xu Zhang, Zhiwei Wang, Bingteng Xie, Tinglu Song, Fulai Zhang, Aiqin Luo, Shanshan Li, Xiaolu Xiong, Junfeng Han
论文因子:7.571 发表期刊:Journal of Materials Chemistry B pmid:36537727
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:MicroRNA-181a-5p alleviates acute liver failure in mice by inhibiting HMGB1
成员:Qianwen Zhang, Yiyu He, Hao Xu, Yuqiao Zeng, Li Wang, Zengxi Xue, Qingyun Sun, Likun Wang
论文因子:1.6 发表期刊:CELLULAR AND MOLECULAR BIOLOGY pmid:37807324
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Nuclear translocation of PKM2 mediates keratinocyte metabolic reprogramming in psoriasis
成员:Luting Yang, Jie Zhang, Chunqing Hu, Xiaowen Chen, Yang Yang, Huihao Tang, Xiaolei Ding, Yaping Yan
论文因子:3.6 发表期刊:EXPERIMENTAL DERMATOLOGY pmid:37688280
| 基本信息 | |
| 基因名 | |
| 别名 | Tumor Necrosis Factor;Cachectin;TNF-Alpha;Tumor Necrosis Factor Ligand Superfamily Member2;TNF-a;TNF;TNFA;TNFSF2 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0. |
| 溶解性 | Solube in water |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 区间范围 | MVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISR IAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL |
| 背景说明 | TNFα is a homotrimer with a subunit molecular mass of 17 kD cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR.It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines.It plays a major role in growth regulation，differentiation，inflammation，viral replication，tumorigenesis，autoimmune diseases and in viral，bacterial，fungal，and parasitic infections.Besides inducing hemorrhagic necrosis of tumors，TNF was found to be involved in tumorigenesis，tumor metastasis，viral replication，septic shock，fever，inflammation，and autoimmune diseases including Crohn’s disease，and rheumatoid arthritis as well as graft-versus-host disease. |
| 来源 | E.coli |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/μg(1 EU/μg)as determined by LAL test. |
| 单位 | 支 |
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文献和实验【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Loss-of-function mutations in Keratin 32 gene disrupt skin immune homeostasis in pityriasis rubra pilaris
成员:Shi Peidian, Chen Wenjie, Lyu Xinxing, Wang Zhenzhen, Li Wenchao, Jia Fengming, Zheng Chunzhi, Liu Tingting, Wang Chuan, Zhang Yuan, Mi Zihao, Sun Yonghu, Chen Xuechao, Chen Shengli, Zhou Guizhi, Liu Yongxia, Lin Yingjie, Bai Fuxiang, Sun Qing, Ogese Mond
论文因子:14.7 发表期刊:Nature Communications pmid:39048559
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Triptolide mitigates the inhibition of osteogenesis induced by TNF-α in human periodontal ligament stem cells via the p-IκBα/NF-κB signaling pathway: an in-vitro study
成员:Chen Hao, Zhang Lina, Du Simeng, Yang Daiwei, Cui Xiaobin, Zhao Huadong, Zhang Jun
论文因子:3.9 发表期刊:BMC Complementary Medicine and Therapies pmid:38448925
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Topological insulator Bi2Se3 based electrochemical aptasensors for the application of sensitive detection of interferon-γ
成员:Yetong Wu, Peng Zhu, Yujiu Jiang, Xu Zhang, Zhiwei Wang, Bingteng Xie, Tinglu Song, Fulai Zhang, Aiqin Luo, Shanshan Li, Xiaolu Xiong, Junfeng Han
论文因子:7.571 发表期刊:Journal of Materials Chemistry B pmid:36537727
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:MicroRNA-181a-5p alleviates acute liver failure in mice by inhibiting HMGB1
成员:Qianwen Zhang, Yiyu He, Hao Xu, Yuqiao Zeng, Li Wang, Zengxi Xue, Qingyun Sun, Likun Wang
论文因子:1.6 发表期刊:CELLULAR AND MOLECULAR BIOLOGY pmid:37807324
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Nuclear translocation of PKM2 mediates keratinocyte metabolic reprogramming in psoriasis
成员:Luting Yang, Jie Zhang, Chunqing Hu, Xiaowen Chen, Yang Yang, Huihao Tang, Xiaolei Ding, Yaping Yan
论文因子:3.6 发表期刊:EXPERIMENTAL DERMATOLOGY pmid:37688280
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