Cyfluthrin

拟除虫菊酯杀虫剂；调节Nav通道；缓慢激活在非洲爪蟾卵母细胞中表达的重组大鼠Nav1.8并延迟失活；降低大鼠原代神经元的平均爆发率（IC50分别为0.99μM）；对多种昆虫有毒性，包括A.melinus、G.ashmeadi、E.eremicus和E.formosa（LC50分别为7、67、96和63ng/ml）和A.sinensis蚊子（LC50=0.446ppm）；对A.mellifera蜜蜂有毒性（LD50=0.22ppm），在10ng/只蜜蜂的剂量下影响运动活动和翅膀扇动行为。A pyrethroid insecticide; modulates Nav channels; slowly activates recombinant rat Nav1.8 expressed in Xenopus oocytes and delays inactivation; decreases the mean burst rate in rat primary neurons (IC50 = 0.99 μM, respectively); toxic to various insects, including A. melinus, G. ashmeadi, E. eremicus, and E. formosa (LC50s = 7, 67, 96, and 63 ng/ml, respectively) and the A. sinensis mosquito (LC50 = 0.446 ppm); toxic to A. mellifera honeybees (LD50 = 0.22 ppm), affecting locomotor activity and wing fanning behavior at 10 ng/bee.