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文献和实验Chemokine control of HIV-1 infection
underlying viral entry and tropism 4 . The virus strains responsible for transmission, which are the predominant virus type isolated from asymptomatic HIV-positive individuals, use CCR5 as a receptor, whereas viruses that emerge later in the course
Cell Cycle Checkpoint Control Mechanisms That Can Be Disrupted in Cancer
. Multiple checkpoints exist and are conserved in the cell cycle in higher eukaryotes to ensure that if one fails, others will take care of genomic integrity and cell survival. Many genes act as either positive or negative regulators of checkpoint function
A chemokine-driven positive feedback loop organizes lymphoid follicles
, establishing a positive feedback loop that is likely to be important in follicle development and homeostasis. In germinal centres the feedback loop is overridden, with B-cell lymphotoxin 1 2 expression being induced by a mechanism
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