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文献和实验Detection of Calcium Release via Ryanodine Receptors
The ryanodine receptor ion channels (RyRs) release Ca2+ from the endo/sarcoplasmic reticulum in a variety of nonvertebrate and vertebrate species including flies, crustaceans, birds, fish, and amphibians. They are most abundant in skeletal
has been identified as a high-affinity receptor for the plant alkaloid ryanodine, and purified to apparent homogeneity as a 30s protein complex comprising four identical high- mol-wt polypeptide subunits of relative mol mass (M r ) ~560,000 (it1
Aspects of CNS Lupus: Mouse Models of Anti-NMDA Receptor Antibody Mediated Reactivity
This chapter describes methods utilized in establishing a mouse model of neuropsychiatric lupus encompassing both cognitive and emotional dysfunction, and a model of the influence of maternal antibody on the developing brain. The antibody
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