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IGF-I/Somatamedin C/IGF-IA,Mou

se,Recombinant
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  • ¥500 - 8280
  • 普诺赛
  • PCK018
  • 国产
  • 2025年07月31日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现货

    • 供应商

      上海经科化学科技有限公司

    • 规格

      1mg/50μg/500μg/10μg

    规格:1mg产品价格:¥8280.0
    规格:50μg产品价格:¥780.0
    规格:500μg产品价格:¥5880.0
    规格:10μg产品价格:¥500.0

    产品信息

    别名 Somatamedin C, IGF-IA
    物种 Mouse
    表达宿主 E.coli
    序列信息 MGPETLCGAELVDALQFVCGPRGFYFNKPTGYG,S.SIRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPTKAA with polyhistidine tag at the C-terminus.
    检索号 P05017.2
    分子量 8.61 kDa
    表观分子量 11-17 kDa
    标签 His-tag at the C-terminus
    生物活性 Measure by its ability to induce MCF-7 cells proliferation.The ED50 for this effect is <2 ng/mL.The specific activity of recombinant mouse IGF-I is > 5 x 10^5 IU/mg.

    产品特性

    纯度 >98% as determined by SDS-PAGE. Ni-NTA chromatography
    内毒素 <0.1 EU per 1 μg of the protein by the LAL method.
    保存 Lyophilized protein should be stored at -5~-20°C for 1 year. Upon reconstitution,store at 2-8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g.0.1% BSA,10%FBS,5%HSA or 5% trehalose solution), protein aliquots should be stored at -5~-20°C or -80°C for 3-6 months.
    运输 Ambient temperature or ice pack.
    制剂 The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 8.0.
    复融 It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL.Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.

    背景介绍

    Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a protein that in humans is encoded by the IGF1 gene. IGF-1 is a hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults. A synthetic analog of IGF-1, mecasermin, is used for the treatment of growth failure.

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