IL-1RAcP/ IL-1R3/ IL-1F6 (C-Fc-6His), Human, Recombinant

IL-1RAcP/ IL-1R3/ IL-1F6 (C-Fc

-6His), Human, Recombinant
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  • ¥780 - 12380
  • 普诺赛
  • PCK143
  • 国产
  • 2025年07月29日
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    • 详细信息
    • 技术资料
    • 库存

      现货

    • 供应商

      上海经科化学科技有限公司

    • 规格

      50μg/1mg/10μg/500μg

    规格:50μg产品价格:¥1380.0
    规格:1mg产品价格:¥12380.0
    规格:10μg产品价格:¥780.0
    规格:500μg产品价格:¥7880.0

    产品信息

    别名 Interleukin-1 Receptor Accessory Protein; IL-1 Receptor Accessory Protein; IL-1RAcP; Interleukin-1 Receptor 3; IL-1R-3; IL-1R3; IL1RAP; C3orf13; IL1R3
    物种 Human
    表达宿主 Human Cells
    序列信息 Ser21-Gln356
    检索号 Q9NPH3-2
    分子量 66.7 kDa
    表观分子量 80-100 kDa
    标签 C-Fc-6His

    产品特性

    纯度 >95% as determined by reducing SDS-PAGE.
    内毒素 < 1.0 EU per µg as determined by LAL test.
    保存 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
    运输 Ambient temperature or ice pack.
    制剂 Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .
    复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    背景介绍

    Interleukin-1 Receptor Accessory Protein (IL-1RAcP) is a member of the Interleukin-1 Receptor family. It contains three Ig-like C2-type domains in the extracellular region and a long cytoplasmic domain implicated in signal transduction. IL-1RAcP acts as a non-Ligand binding accessory component of the Receptors for IL1α, IL1βand IL33. IL-1RAcP mediates Interleukin-1-dependent activation of NF-kappa-B. It is part of the membrane-bound form of the IL-1 Receptor. IL-1 RAcP takes part in the Signaling ways by the formation of a ternary complex containing IL1R1, TOLLIP, MYD88, and IRAK1 or IRAK2. In addition, IL-1RAcP modulates the response to Interleukins by associating with soluble IL1R1 and enhancing Interleukin-binding to the decoy Receptor.

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    IL-1RAcP/ IL-1R3/ IL-1F6 (C-Fc-6His), Human, Recombinant
    ¥780 - 12380