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CXCL5/ENA-78,Human,Recombinant

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  • ¥1280 - 25680
  • 普诺赛
  • PCK127
  • 国产
  • 2025年07月29日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现货

    • 供应商

      上海经科化学科技有限公司

    • 规格

      500μg/50μg/1mg/10μg

    规格:500μg产品价格:¥17480.0
    规格:50μg产品价格:¥3280.0
    规格:1mg产品价格:¥25680.0
    规格:10μg产品价格:¥1280.0

    产品信息

    别名 Epithelial Neutrophil Activating Peptide-78, ENA-78
    物种 Human
    表达宿主 E.coli
    序列信息 RELRCVCLQTTQGVHPKMISNLQVFAIGPQCSKVEVVASLKNGKEICLDPEAPFLKKVIQKILDGGNKEN with polyhistidine tag at the N-terminus.
    检索号 P42830
    分子量 8.51 kDa
    表观分子量 12 kDa
    标签 His-tag at the N-terminus
    生物活性 Measure by its ability to chemoattract BaF3 cells transfected with human CXCR2. The ED50 for this effect is <10 ng/mL.

    产品特性

    纯度 >98% as determined by SDS-PAGE. Ni-NTA chromatography
    内毒素 <0.1 EU per 1 μg of the protein by the LAL method.
    保存 Lyophilized protein should be stored at -5~-20°C for 1 year. Upon reconstitution,store at 2-8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g.0.1% BSA,10%FBS,5%HSA or 5% trehalose solution), protein aliquots should be stored at -5~-20°C or -80°C for 3-6 months.
    运输 Ambient temperature or ice pack.
    制剂 The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4.
    复融 It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL.Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.

    背景介绍

    The protein encoded by this gene, Chemokine (C-X-C motif) ligand 5 (CXCL5), is a small cytokine belonging to the CXC chemokine family that is also known as epithelial-derived neutrophil-activating peptide 78 (ENA-78). This chemokine is produced concomitantly with interleukin-8 (IL8) in response to stimulation with either interleukin-1 (IL1) or tumor necrosis factor-alpha (TNFA). It is observed that, CXCL5 also expresses in eosinophils, and can interact with the type II interferon IFN-?, thereby cause an inhibition. This chemokine stimulates the chemotaxis of neutrophils possesses angiogenic properties, and elicits these effects by interacting with the cell surface chemokine receptor CXCR2.

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