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TNFR2/ TNFRSF1B/ CD120b (C-6Hi

s), Human, Recombinant
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  • ¥1380 - 25680
  • 普诺赛
  • PCK221
  • 国产
  • 2025年07月30日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现货

    • 供应商

      上海经科化学科技有限公司

    • 规格

      50μg/1mg/500μg/10μg

    规格:50μg产品价格:¥3680.0
    规格:1mg产品价格:¥25680.0
    规格:500μg产品价格:¥17480.0
    规格:10μg产品价格:¥1380.0

    产品信息

    别名 Tumor necrosis factor Receptor superfamily member 1B; Tumor necrosis factor Receptor 2; Tumor necrosis factor Receptor type II; p75; p80 TNF-alpha Receptor; TBP-2; TBPII; TNFRSF1B; TNFBR; TNFR2
    物种 Human
    表达宿主 Human Cells
    序列信息 Leu23-Asp257
    检索号 P20333
    分子量 26.2 kDa
    表观分子量 40 kDa

    产品特性

    纯度 >95% as determined by reducing SDS-PAGE.
    内毒素 < 1.0 EU per µg as determined by LAL test.
    保存 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
    运输 Ambient temperature or ice pack.
    制剂 Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
    复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    背景介绍

    Tumor necrosis factor Receptor superfamily member 1B is a 461 amino acids Protein that belongs to the TNFR (tumor necrosis factor Receptor) superfamily characterized by cysteine-rich extracellular domains. It contains 4 TNFR-Cys repeats. TNFRII is expressed in fetal brain. TNFRII is strongly expressed at the cartilage-pannus junction, and plays a major role in a subset of families with multiple cases of rheumatoid arthritis (RA). This Receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.

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