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- Elabscience
- 湖北武汉
- E-AB-F1403D
- 2025年07月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
- 保质期：
12个月
- 库存：
999
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 抗体英文名：
PE Anti-Mouse CD20 Antibody[SA271G2]
- 规格：
100Tests/50Tests/100Tests×2
| 规格： | 100Tests | 产品价格： | ￥1176.0 |
|---|---|---|---|
| 规格： | 50Tests | 产品价格： | ￥648.0 |
| 规格： | 100Tests×2 | 产品价格： | ￥2112.0 |
产品名称：PE Anti-Mouse CD20 Antibody[SA271G2]
货号：E-AB-F1403D
| Background |
CD20 is a 33-37 kD protein, a member of the MS4A family, with four transmembrane spanning regions that present as a homo-oligomeric complexes in the cell surface when associating with MHC class I and II, CD53, CD81, and CD82. CD20 is expressed on B cells and a subset of T cells, but not on plasma cells. CD20 regulates B-cell activation and proliferation. Its ligation promotes transmembrane Ca2+ trafficking. CD20 is an important therapeutic target in the treatment of B cell lymphomas and leukemias.
|
| Swissprot |
P19437
|
| Gene ID |
12482
|
| Clone No |
SA271G2
|
| Host |
Rat
|
| Reactivity |
Mouse
|
| Application |
FCM
|
| Isotype |
Rat IgG2b;κ
|
| Isotype Control |
PE Rat IgG2b, κ Isotype Control[LTF-2]
|
| Conjugation |
PE
|
| Conjugation Information |
PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
|
| Spectrum |
|
| Storage Buffer |
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
|
| Storage |
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
|
| Expiration date |
12个月
|
| Shipping |
冰袋
|
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文献和实验membrane, creating a structure similar to an ion channel Delivers early signal in B cell activation, allowing resting B cells to respond to later antigens Rituximab is a chimeric murine-human anti-CD20 antibody used for treatment of B cell
T-cell dependent antigen specific in situ staining (Pe)
6- Wash twice in TBS-T. 7- counterstain with rabbit anti B-Pe 1:2000 (0.5 µg/ml Cortex Biochem). You may add 1% mouse serum to the anti-Pe antibodies, unless you plan to use mouse monoclonal further (see below). 8- wash twice in TBS-T. 9- block
of a mouse-human chimeric monoclonal antibody to Cd20 with potent Fc-dependent biologic activity. J.Immunol.，1987，139：3521[4]Press ow，Farr AG，Borroz KI，et al. Endocytosis and degradation of monoclonal antibodies targeting human B-celll malignancies. Cancer
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