CD45R

CD45R

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  • ¥1280 - 2180
  • Tanda
  • 中国
  • TD-31935
  • 2025年11月19日
  • FCM、ELISA、IHC、WB、ICC
  • Mouse
  • Human
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    • 详细信息
    • 技术资料
    • 免疫原

      peptide

    • 亚型

      IgG1

    • 形态

      Liquid

    • 保存条件

      -20℃

    • 克隆性

      mAb

    • 适应物种

      Human

    • 保质期

      1年

    • 目录编号

      TD-31935

    • 级别

      科研级

    • 库存

      88

    • 供应商

      武汉天德

    • 宿主

      Mouse

    • 应用范围

      FCM、ELISA、IHC、WB、ICC

    • 靶点

      详询

    • 抗体英文名

      Mouse Monoclonal Antibody to CD45R

    • 抗体名

      CD45R

    • 规格

      100ul/50ul

    规格:100ul产品价格:¥2180.0
    规格:50ul产品价格:¥1280.0

    Mouse Monoclonal Antibody to CD45R

    Description

    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.

    Specification

    Aliases PTPRC; LCA; LY5; B220; L-CA; T200; CD45; GP180
    Entrez GeneID 5788
    Swissprot P08575
    clone 2H3E2
    WB Predicted band size 147.5kDa
    Host/Isotype Mouse IgG1
    Antibody Type Primary antibody
    Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
    Species Reactivity Human, Mouse, Rat
    Immunogen Purified recombinant fragment of human CD45R (AA: extra 378-577) expressed in E. Coli.
    Formulation Purified antibody in PBS with 0.05% sodium azide

    Application

    WB 1/500 - 1/2000
    IHC 1/200-1/1000
    ICC 1/200 - 1/1000
    FCM 1/200-1/400
    ELISA 1/10000

    Product Image

    • CD45R
      Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)
    • CD45R
      Western blot analysis using CD45R mouse mAb against Jurkat (1), Rat Serum (2), and mouse Serum (3) cell lysate.
    • CD45R
      Immunofluorescence analysis of Hela cells using CD45R mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
    • CD45R
      Flow cytometric analysis of Hela cells using CD45R mouse mAb (green) and negative control (red).
    • CD45R
      Flow cytometric analysis of Jurkat cells using CD45R mouse mAb (green) and negative control (red).
    • CD45R
      Immunohistochemical analysis of paraffin-embedded human tonsil tissues using CD45R mouse mAb with DAB staining.
    • CD45R
      Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using CD45R mouse mAb with DAB staining.
     
     

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