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- 详细信息
- 文献和实验
- 技术资料
- 英文名:
CDK12 inhibitor 2
- 库存:
期货
- 供应商:
上海阿拉丁生化科技股份有限公司
- 规格:
C608435-5mg/C608435-25mg
| 规格: | C608435-5mg | 产品价格: | ¥2599.9 |
|---|---|---|---|
| 规格: | C608435-25mg | 产品价格: | ¥5999.9 |
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文献和实验Functional Analysis of CDK Inhibitor p21WAF1
p21WAF1 was originally identified as a protein that binds and inhibits cyclin-dependent kinases (CDKs). p21WAF1 is recognized to have at least two separate roles—first as a CDK inhibitor, and second as an inhibitor of PCNA, an accessory
-amylases of diverse origin. Three major groups of α-amylase have been characterized, based on molecular weight: 60,000, 24,000, and 12,500 Da. The inhibitor forms a complex with amylase. The complex formation can inactivate the amylase and in turn cause
. Similar biphasic pattern of JNK activation is also observed in the parental PC12 cells. Using the specific JNK inhibitor SP600125, we show that the biphasic activation is necessary for neurite outgrowth and branching, and that inhibition
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