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- Biorbyt
- 英国
- orb2279085
- 2026年08月07日
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- 文献和实验
- 技术资料
- 保存条件：
详询
- 保质期：
12 months from date of receipt.
- 英文名：
MC-Val-Cit-PAB-Exatecan
- 库存：
99
- 供应商：
Biorbyt
- CAS号：
2504068-28-2
- 规格：
1 mg/5 mg/10 mg/25 mg
| 规格： | 1 mg | 产品价格： | ￥1053.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥1638.0 |
| 规格： | 10 mg | 产品价格： | ￥2457.0 |
| 规格： | 25 mg | 产品价格： | ￥4446.0 |
类别: Small Molecules
描述: MC-Val-Cit-PAB-Exatecan is a cathepsin-cleavable drug-linker conjugate incorporating the potent topoisomerase I inhibitor DX-8951 (Exatecan). It is designed for constructing antibody-drug conjugates (ADCs) and is used in research to evaluate targeted cytotoxicity in both in vitro and in vivo cancer models.
别名: DrugLinkerConjugatesforADC, DrugLinker Conjugates for ADC, MC-Val-Cit-PAB-DX 8951, MC-Val-Cit-PAB-DX8951, MC-Val-Cit-PAB-DX-8951, MC-Val-Cit-PAB-Exatecan
靶点: Topoisomerase,Drug-Linker Conjugates for ADC
分子式: C53H60FN9O12
分子量: 1034.09
纯度: 98.03% (May vary between batches)
SMILES: N(C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(CCCCCN2C(=O)C=CC2=O)=O)[C@H](C)C)=O)CCCNC(N)=O)=O)C=C1)=O)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(F)C8
溶解度: DMSO:80 mg/mL (77.36 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (0.97 mM)
研究领域: Molecular Biology, Pharmacology & Drug Discovery
保存条件: -20°C
备注: For research use only.
描述: MC-Val-Cit-PAB-Exatecan is a cathepsin-cleavable drug-linker conjugate incorporating the potent topoisomerase I inhibitor DX-8951 (Exatecan). It is designed for constructing antibody-drug conjugates (ADCs) and is used in research to evaluate targeted cytotoxicity in both in vitro and in vivo cancer models.
别名: DrugLinkerConjugatesforADC, DrugLinker Conjugates for ADC, MC-Val-Cit-PAB-DX 8951, MC-Val-Cit-PAB-DX8951, MC-Val-Cit-PAB-DX-8951, MC-Val-Cit-PAB-Exatecan
靶点: Topoisomerase,Drug-Linker Conjugates for ADC
分子式: C53H60FN9O12
分子量: 1034.09
纯度: 98.03% (May vary between batches)
SMILES: N(C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(CCCCCN2C(=O)C=CC2=O)=O)[C@H](C)C)=O)CCCNC(N)=O)=O)C=C1)=O)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(F)C8
溶解度: DMSO:80 mg/mL (77.36 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (0.97 mM)
研究领域: Molecular Biology, Pharmacology & Drug Discovery
保存条件: -20°C
备注: For research use only.
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文献和实验相关实验
for ADC MC-Val-Cit-PAB (HY-78738) www.medchemexpress.cn/MC-Val-Cit-PAB.html ADC Protease Cleavable Linker DBCO-Val-Cit-PABC-PNP (HY-130937) www.medchemexpress.cn/dbco-val-cit-pabc-pnp.html ADC Protease Cleavable Linker
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MC-Val-Cit-PAB-Exatecan，orb2279085，Biorbyt
￥1053 - 4446
