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- Biorbyt
- 英国
- orb2279052
- 2026年08月07日
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- 文献和实验
- 技术资料
- 保存条件：
详询
- 保质期：
12 months from date of receipt.
- 英文名：
Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan
- 库存：
99
- 供应商：
Biorbyt
- CAS号：
1599439-54-9
- 规格：
5 mg
类别: Small Molecules
描述: This maleimide-PEG2-tetrapeptide linker-drug conjugate incorporates the topoisomerase I inhibitor Exatecan, enabling the synthesis of antibody-drug conjugates (ADCs) for targeted cancer therapy research. It is applied in both in vitro cytotoxicity assays and in vivo preclinical studies to evaluate ADC efficacy and payload delivery.
靶点: Drug-Linker Conjugates for ADC,Topoisomerase
分子式: C57H65FN10O15
分子量: 1149.18
SMILES: N(C(CCCNC(CNC([C@H](CC1=CC=CC=C1)NC(CNC(CNC(CCOCCOCCNC(CCN2C(=O)C=CC2=O)=O)=O)=O)=O)=O)=O)=O)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(F)C8
研究领域: Metabolism Research; Pharmacology & Drug Discovery, Molecular Biology
保存条件: -20°C
备注: For research use only.
描述: This maleimide-PEG2-tetrapeptide linker-drug conjugate incorporates the topoisomerase I inhibitor Exatecan, enabling the synthesis of antibody-drug conjugates (ADCs) for targeted cancer therapy research. It is applied in both in vitro cytotoxicity assays and in vivo preclinical studies to evaluate ADC efficacy and payload delivery.
靶点: Drug-Linker Conjugates for ADC,Topoisomerase
分子式: C57H65FN10O15
分子量: 1149.18
SMILES: N(C(CCCNC(CNC([C@H](CC1=CC=CC=C1)NC(CNC(CNC(CCOCCOCCNC(CCN2C(=O)C=CC2=O)=O)=O)=O)=O)=O)=O)=O)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(F)C8
研究领域: Metabolism Research; Pharmacology & Drug Discovery, Molecular Biology
保存条件: -20°C
备注: For research use only.
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文献和实验相关实验
Mc-Val-Ala-PAB (HY-126364) www.medchemexpress.cn/mc-val-ala-pab.html ADC Protease Cleavable Linker Mc-Gly-Gly-Phe-Gly-PAB-OH (HY-136432) www.medchemexpress.cn/mc-gly-gly-phe-gly-pab-oh.html ADC Protease Cleavable Linker
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Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan，orb2279052，Biorbyt
￥5967
