- ￥0
- Biorbyt
- 英国
- orb2277696
- 2026年08月07日
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- 文献和实验
- 技术资料
- 保存条件：
详询
- 保质期：
12 months from date of receipt.
- 英文名：
Antibacterial agent 159
- 库存：
99
- 供应商：
Biorbyt
- CAS号：
2804044-53-7
- 规格：
5 mg/50 mg
| 规格： | 5 mg | 产品价格： | ￥0.0 |
|---|---|---|---|
| 规格： | 50 mg | 产品价格： | ￥0.0 |
描述: Compound 6d (Antibacterial agent 159) is a small-molecule antibiotic effective for research on impetigo and Clostridium difficile infection (CDI). It demonstrates promising in vivo efficacy with low recurrence rates for CDI and shows minimal disruption to the commensal gut microbiota in preclinical studies.
靶点: Antibiotic
分子式: C51H50N16O10S6
分子量: 1239.43
SMILES: O=[N+](C1=CN=C(C)N1CCNC(/C(NC(C2=CSC(C3=CSC(C4=CC=C(C5=NC(C(N[C@@](C(N/C(C6=NC(C(N[C@H](C7=NC(C(N8)=O)=CS7)C(C)C)=O)=CS6)=C\C)=O)([H])[C@H](O)C)=O)=CS5)C(C9=CSC([C@]8([H])[C@H](O)C)=N9)=N4)=N3)=N2)=O)=C/C)=O)[O-]
研究领域: Infectious Disease & Virology
保存条件: -20°C
备注: For research use only.
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文献和实验Genomic Approaches to Antibacterial Discovery
of concept in curing experimental infections. The second approach is based on screening for compounds with antibacterial activity and then employing a broad variety of newer technologies to identify the molecular target of the antibacterial agent
Methods to Assay Inhibitors of tRNA Synthetase Activity
could be a potential antibacterial agent. Only one aa-RS inhibitor, the Ile-RS inhibitor mupirocin, is currently marketed as an antibacterial agent. We focused on phenylalanyl (Phe)-tRNA synthetase (Phe-RS), but the described methods are not restricted to Phe-RS
Assessing the Activity of Bacterial Multidrug Efflux Pumps
Resistance to antibiotics in target bacterial populations has long complicated antibacterial chemotherapy. First described in the early 1980s (1 , 2 ), efflux mechanism of resistance, whereby the antibiotic is actively (i.e., in an energy
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