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- Biorbyt
- 英国
- orb2277587
- 2026年08月07日
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- 技术资料
- 保存条件：
详询
- 保质期：
12 months from date of receipt.
- 英文名：
DBt-10
- 库存：
99
- 供应商：
Biorbyt
- 规格：
50 mg/5 mg
| 规格： | 50 mg | 产品价格： | ￥0.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥0.0 |
类别: Small Molecules
描述: DBt-10 is a potent and selective small molecule degrader of Bruton's tyrosine kinase (BTK). It facilitates the targeted proteasomal degradation of BTK, making it a valuable chemical probe for investigating BTK-dependent signaling pathways in both cellular (in vitro) and animal (in vivo) models of B-cell malignancies and autoimmune diseases.
靶点: PROTACs,BTK
分子式: C68H86ClFN16O6
分子量: 1277.96
SMILES: NCCNC1=NC(C2(CCCCC2)C3=CC=C(Cl)C=C3)=NC4=C1C=CC(N5CCN(C(CCCC(NCCN6CCOC7(CCN(C(CN8N=CC(C9=CC(C(C%10=C(C)C(NC(N%11CC(CC(C)(C)C)(O)C%11)=O)=CC(F)=C%10)=NC=N%12)=C%12N9)=C8)=O)CC7)C6)=O)=O)CC5)=C4
研究领域: Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
保存条件: -20°C
备注: For research use only.
描述: DBt-10 is a potent and selective small molecule degrader of Bruton's tyrosine kinase (BTK). It facilitates the targeted proteasomal degradation of BTK, making it a valuable chemical probe for investigating BTK-dependent signaling pathways in both cellular (in vitro) and animal (in vivo) models of B-cell malignancies and autoimmune diseases.
靶点: PROTACs,BTK
分子式: C68H86ClFN16O6
分子量: 1277.96
SMILES: NCCNC1=NC(C2(CCCCC2)C3=CC=C(Cl)C=C3)=NC4=C1C=CC(N5CCN(C(CCCC(NCCN6CCOC7(CCN(C(CN8N=CC(C9=CC(C(C%10=C(C)C(NC(N%11CC(CC(C)(C)C)(O)C%11)=O)=CC(F)=C%10)=NC=N%12)=C%12N9)=C8)=O)CC7)C6)=O)=O)CC5)=C4
研究领域: Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
保存条件: -20°C
备注: For research use only.
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