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Human IL-2 R beta&IL-2 R gamma

Heterodimer
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  • ¥840 - 17600
  • SinoBio
  • 国产
  • C33A
  • 2025年11月10日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      蛋白表达区间:Ala27-Asp239&Leu23-Asn254

    • 保质期

      See instructions

    • 英文名

      标签:C-Fc&C-Fc

    • 库存

      表达系统:Human Cells

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥840.0
    规格:50ug产品价格:¥2520.0
    规格:500ug产品价格:¥12320.0
    规格:1mg产品价格:¥17600.0
    产品描述
    Recombinant Human IL-2 R beta&IL-2 R gamma Heterodimer is produced by our Mammalian expression system and the target gene encoding Ala27-Asp239&Leu23-Asn254 is expressed with a human IgG1 Fc knob and human IgG1 Fc hole tag at the C-terminus respectively.
    蛋白编号
    P14784&
    P31785
    产品别称
    IL-2 R beta & IL-2 R gamma,IL-2RB & IL-2RG
    分子量
    54&51 KDa
    表观分子量
    (57-72)&(85-115) KDa, reducing conditions
    剂型描述
    Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
    内毒素
    < 1 EU/µg as determined by LAL test.
    纯度-SDS-PAGE
    Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
    生物活性-BLI
    Loaded Recombinant Human IL-2 R beta&IL-2 R gamma Heterodimer Protein (C-Fc)(Cat#C33A) on Pro-A Biosensor, can bind Recombinant Human IL-2 (C-6His) (Cat#CX66) with an affinity constant of 1.50 nM as determined in BLI assay. (Regularly tested)
    复溶
    • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    • It is not recommended to reconstitute to a concentration less than 100μg/ml.
    • Dissolve the lyophilized protein in distilled water.
    • Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
    运输条件
    • The product is shipped at ambient temperature.
    • Upon receipt, store it immediately at the temperature listed below.
    保存条件
    • Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
    • Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
    • Aliquots of reconstituted samples are stable at ≤ -20°C for 1 months.
    产品背景
    The interleukin 2 (IL-2) receptor (IL-2R) is a multisubunit receptor that includes three major IL-2 binding subunits, the IL-2R alpha, beta, and gamma chains. We have detected and analyzed cooperative interactions between the IL-2R alpha and beta chains (IL-2R alpha and IL-2R beta, respectively) in COS cells transfected with cDNAs encoding the IL-2R alpha, the IL-2R beta, or both cDNAs.The affinities of Neo-2/15 for the human and mouse IL-2 receptors (IL-2Rβ and IL-2Rβγc) are significantly higher than those of the corresponding native IL-2 cytokines. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.

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    图标文献和实验
    该产品被引用文献

    The interleukin 2 (IL-2) receptor (IL-2R) is a multisubunit receptor that includes three major IL-2 binding subunits, the IL-2R alpha, beta, and gamma chains. We have detected and analyzed cooperative interactions between the IL-2R alpha and beta chains (IL-2R alpha and IL-2R beta, respectively) in COS cells transfected with cDNAs encoding the IL-2R alpha, the IL-2R beta, or both cDNAs.The affinities of Neo-2/15 for the human and mouse IL-2 receptors (IL-2Rβ and IL-2Rβγc) are significantly higher than those of the corresponding native IL-2 cytokines. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.

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    文献支持
    Human IL-2 R beta&IL-2 R gamma Heterodimer
    ¥840 - 17600