AZDye 647吡啶甲基Azide-5 mg-AZDye

AZDye 647吡啶甲基Azide-5 mg，AZDye 647 Picolyl Azide-5 mg，AZDye 647吡啶甲基Azide-5 mg,AZDye 647 Picolyl Azide-5 mg

AZDye 647吡啶甲基Azide-5 mg-AZDye 647 Picolyl Azide-5 mg

产品货号：CCT-1300-5

产品规格：5mg

AZDye™ 647 Picolyl Azide是一种先进的荧光探针，它结合了铜螯合基序，以提高反应位点处Cu(I)的有效浓度，从而提高CuAAC反应的效率，从而实现更快、更生物相容的CuAAC标记。据报道，与常规叠氮化物相比，信号强度增加高达40倍。

AZDye™ 647 Picolyl Azide is an advanced fluorescent probe that incorporates a copper-chelating motif to raise the effective concentration of Cu(I) at the reaction site to boost the efficiency of the CuAAC reaction, resulting in a faster and more biocompatible CuAAC labeling. Up to 40-fold increase of signal intensity, compared to conventional azides, was reported.In addition, the use picolyl azides instead of conventional azides allows for at least a tenfold reduction in the concentration of the copper catalyst without sacrificing the efficiency of labeling, significantly improving biocompatibility of CuAAC labeling protocol.In summary, the introduction of a copper-chelating motif into azide probe leads to a substantial increase in the sensitivity and reduced cell toxicity of CuAAC detection alkyne-tagged biomolecules. This will be of special value for the detection of low abundance targets or living system imaging.AZDye™ 647 Picolyl Azide is a water-soluble, pH-insensitive from pH 4 to pH 10, far-red-fluorescent probe with excitation ideally suited for the 633 nm or 647 nm laser lines. AZDye™ 647 is structurally similar to Alexa Fluor® 647, and spectrally is almost identical to Cy5 Dye, Alexa Fluor® 647, CF® 647 Dye, or any other Cyanine5 based fluorescent dyes. Alexa Fluor® is a registered trademark of Thermo Fisher Scientific.

AZDye 647吡啶甲基Azide-5 mg-AZDye 647 Picolyl Azide-5 mg-20°C. Desiccate

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