AZDye 594Azide吡啶-1 mg-AZDye 59

AZDye 594Azide吡啶-1 mg，AZDye 594 Picolyl Azide-1 mg，AZDye 594Azide吡啶-1 mg,AZDye 594 Picolyl Azide-1 mg

AZDye 594Azide吡啶-1 mg-AZDye 594 Picolyl Azide-1 mg

产品货号：CCT-1296-1

产品规格：1mg

AZDye™ 594 Picolyl Azide是一种先进的荧光探针，它结合了铜螯合基序，以提高反应位点处Cu(I)的有效浓度，从而提高CuAAC反应的效率，从而实现更快、更生物相容的CuAAC标记。据报道，与常规叠氮化物相比，信号强度增加高达40倍。

AZDye™ 594 Picolyl Azide is an advanced fluorescent probe that incorporates a copper-chelating motif to raise the effective concentration of Cu(I) at the reaction site to boost the efficiency of the CuAAC reaction, resulting in a faster and more biocompatible CuAAC labeling. Up to 40-fold increase of signal intensity, compared to conventional azides, was reported.In addition, the use picolyl azides instead of conventional azides allows for at least a tenfold reduction in the concentration of the copper catalyst without sacrificing the efficiency of labeling, significantly improving biocompatibility of CuAAC labeling protocol.In summary, the introduction of a copper-chelating motif into azide probe leads to a substantial increase in the sensitivity and reduced cell toxicity of CuAAC detection alkyne-tagged biomolecules. This will be of special value for the detection of low abundance targets or living system imaging.AZDye™ 594 is bright, water-soluble, and pH-insensitive from pH 4 to pH 10 red-fluorescent dye with absorption and emission maxima at 590 and 617 nm, respectively. It can be used with the 561 nm and 594 nm laser lines. AZDye™ 594 dye structurally is identical to Alexa Fluor® 594. Its absorption/emission spectra is a perfect match to spectra of many other fluorescent dyes based on sulfonated rhodamine core, including CF® 594 Dye, DyLight® 594 and Alexa Fluor® 594.Alexa Fluor® and DyLight® are registered trademarks of Thermo Fisher Scientific.

AZDye 594Azide吡啶-1 mg-AZDye 594 Picolyl Azide-1 mg-20°C. Desiccate

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