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- 详细信息
- 文献和实验
- 技术资料
- 保质期:
2年
- 英文名:
Bromoacetamido-dPEG®₃-azide-1000 mg
- 库存:
100
- 供应商:
艾美捷科技
- CAS号:
查看datasheet
Bromoacetamide dPEG ® azide-1000mg,Bromoacetamido-dPEG®₃-azide-1000 mg,Bromoacetamide dPEG ® azide-1000mg,Bromoacetamido-dPEG®₃-azide-1000 mg
Bromoacetamide dPEG ® azide-1000mg-Bromoacetamido-dPEG®₃-azide-1000 mg
产品货号:CCT-QBD-11217-1000
产品规格:1000mg
溴乙酰胺-dPEG ®3-叠氮化物,产品编号QBD-11217,是离散PEG(dPEG®)交联剂,其促进游离硫醇与点击化学炔配偶体在短(16个原子,17.5 μ π ι)单分子量PEG桥上的交联。短的两亲性dPEG®连接体增加了缀合物分子的流体动力学体积并增加了它们的水溶性。柔性的非免疫原性间隔区可以减少或消除肾清除率,并通过dPEG®接头赋予的增加的流体动力学体积来帮助保护缀合物免受调理作用。

Bromoacetamido-dPEG®3-azide, product number QBD-11217, is discrete PEG (dPEG®) crosslinker that facilitates the crosslinking of free thiols with click chemistry alkyne partners across a short (16 atoms, 17.5 Å) single molecular weight PEG bridge.The short, amphiphilic dPEG® linker adds hydrodynamic volume to conjugate molecules and increases their water solubility. The flexible, non-immunogenic spacer can reduce or eliminate renal clearance and help shield conjugates from opsonization through the increased hydrodynamic volume the dPEG® linker imparts.The bromoacetate moiety reacts chemoselectively with free thiols at pH >8.0. It is an alternative to the maleimide group and is used in situations where the target molecule needs to be at a high pH. The azide group reacts with a suitable alkyne partner via metal-catalyzed (Cu, Ru) or strain-promoted (copper-free) click chemistry. Moreover, Bromoacetamido-dPEG®3-azide is stable, unlike MAL-PEG-azide constructs, which are somewhat unstable.

Bromoacetamide dPEG ® azide-1000mg-Bromoacetamido-dPEG®₃-azide-1000 mg
点击:Bromoacetamide dPEG ® azide-1000mg-Bromoacetamido-dPEG®₃-azide-1000 mg查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多Vectorlabs公司Azides(Biotin-Azides)试剂、Bis-sulfone交联试剂、DBCO试剂、TCO试剂、Terminal Alkyne试剂、Tetrazine试剂、标记试剂盒以及分选用底物等。,请点击查看艾美捷特色产品中心。

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