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- 保质期:
2年
- 英文名:
m-dPEG®₃₆-amine-1000 mg
- 库存:
100
- 供应商:
艾美捷科技
- CAS号:
查看datasheet
m-dPEG ®-amine-1000 mg,m-dPEG®₃₆-amine-1000 mg,m-dPEG ®-amine-1000 mg,m-dPEG®₃₆-amine-1000 mg
m-dPEG ®-amine-1000 mg-m-dPEG®₃₆-amine-1000 mg
产品货号:CCT-QBD-10908-1000
产品规格:1000mg
m-dPEG®36-胺,产品编号QBD-10908,是一种非免疫原性的水溶性化学修饰试剂。该产品含有单分子量、离散长度的聚乙二醇(dPEG®)链,一端用甲基封端,另一端用反应性伯胺封端。连接基长度为109个原子(130.0 μ m)。氨基与羧酸(及其活性酯)、醛和酮反应。使氨基与醛或酮反应形成不稳定的亚胺(席夫碱),其可在温和条件下还原成仲胺,从而为缀合物提供更大的稳定性。羧酸或其活性酯与m-dPEG®36-胺反应形成稳定的酰胺键。该产品的用途包括钝化表面和涂覆生物分子。

m-dPEG®36-amine, product number QBD-10908, is a non-immunogenic, water-soluble chemical modification reagent. The product contains a single molecular weight, discrete-length polyethylene glycol (dPEG®) chain terminated on one end with a methyl group and on the other end with a reactive primary amine. The linker length is 109 atoms (130.0 Å). The amino group reacts with carboxylic acids (and their active esters), aldehydes, and ketones. Reacting the amino group with aldehydes or ketones forms a labile imine (Schiff base) that can be reduced to a secondary amine under mild conditions to provide greater stability to the conjugate. Reacting carboxylic acids or their active esters with m-dPEG®36-amine forms stable amide bonds. Uses for this product include passivating surfaces and coating biomolecules.Biomolecules modified with m-dPEG®36-amine display enhanced water solubility, increased hydrodynamic volume, and reduced immunogenicity. This product reacts quickly with active esters of carboxylic acids (for example, NHS esters and TFP esters) to form amide bonds. Also, it forms amide bonds directly with carboxylic acids using the carbodiimide EDC.m-dPEG®36-amine is potentially useful in numerous applications. Such applications include the following:Passivating nanoparticle surfaces, including the surfaces of carbon nanotubes and graphene oxide;Creating a non-immunogenic "stealth" coating for liposomes and micelles;Increasing the hydrodynamic volume of small molecules, including peptides and antibody fragments; and,Increasing the water solubility of hydrophobic molecules.

m-dPEG ®-amine-1000 mg-m-dPEG®₃₆-amine-1000 mg
点击:m-dPEG ®-amine-1000 mg-m-dPEG®₃₆-amine-1000 mg查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多Vectorlabs公司Azides(Biotin-Azides)试剂、Bis-sulfone交联试剂、DBCO试剂、TCO试剂、Terminal Alkyne试剂、Tetrazine试剂、标记试剂盒以及分选用底物等。,请点击查看艾美捷特色产品中心。

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