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- 详细信息
- 文献和实验
- 技术资料
- 保质期:
2年
- 英文名:
SPDP-dPEG®₈-NHS ester-100 mg
- 库存:
100
- 供应商:
艾美捷科技
- CAS号:
查看datasheet
SPDP-dPEG®-NHS酯-100mg,SPDP-dPEG®₈-NHS ester-100 mg,SPDP-dPEG®-NHS酯-100mg,SPDP-dPEG®₈-NHS ester-100 mg
SPDP-dPEG®-NHS酯-100mg-SPDP-dPEG®₈-NHS ester-100 mg
产品货号:CCT-QBD-10376-100
产品规格:100mg
SPDP-dPEG®8-NHS酯,产品号QBD-10376,是一种中等长度(32个原子)、亲水性、非免疫原性、异双功能交联剂,其具有与广泛流行但不幸的是疏水性的SPDP交联剂相同的功能。它在dPEG®8接头的一端含有胺反应性N-羟基琥珀酰亚胺基(NHS)酯,在另一端含有硫醇反应性SPDP(也称为OPSS)反应性基团。与传统SPDP交联剂不同,蛋白质或肽与QBD-10376的过度缀合不会因过度疏水性而导致缀合物沉淀。

SPDP-dPEG®8-NHS ester, product number QBD-10376, is a medium-length (32 atoms), hydrophilic, non-immunogenic, heterobifunctional crosslinker that has the same functionality as the widely popular, but unfortunately hydrophobic, SPDP crosslinker. It contains an amine-reactive N-hydroxysuccinimidyl (NHS) ester on one end of the dPEG®8 linker, and a thiol-reactive SPDP (also known as OPSS) reactive group on the other end.Among the most popular heterobifunctional crosslinking reagents used in bioconjugate chemistry are those compounds that conjugate molecules containing free amine groups with molecules that contain sulfhydryl groups. SPDP (N-succinimidyl 3-(2-pyridyldithio)-propionate) is one of the most popular versions of this type of crosslinker. Unfortunately, SPDP and its popular varieties (LC-SPDP and Sulfo-LC-SPDP) are hydrophobic molecules. When conjugated to biomolecules, care must be taken not to modify the target molecules too much, because this can precipitate the conjugate products.By contrast, SPDP-dPEG®8-NHS ester, product number QBD-10376, is used like SPDP and its related hydrophobic products. However, precautions against overly modifying the target molecule are not necessary. The water-soluble dPEG® product will not cause the resulting conjugates to precipitate due to excessive hydrophobicity.

SPDP-dPEG®-NHS酯-100mg-SPDP-dPEG®₈-NHS ester-100 mg
点击:SPDP-dPEG®-NHS酯-100mg-SPDP-dPEG®₈-NHS ester-100 mg查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多Vectorlabs公司Azides(Biotin-Azides)试剂、Bis-sulfone交联试剂、DBCO试剂、TCO试剂、Terminal Alkyne试剂、Tetrazine试剂、标记试剂盒以及分选用底物等。,请点击查看艾美捷特色产品中心。

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