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- MedChemExpress(MCE)
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- HY-113596
- 2025年12月05日
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- 详细信息
- 技术资料
- 保存条件：
4°C, sealed storage, away from moisture
- 英文名：
Acetyl-CoA trisodium
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- 规格：
1 mg/5 mg/10 mg/25 mg
| 规格： | 1 mg | 产品价格： | ￥545.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥1500.0 |
| 规格： | 10 mg | 产品价格： | ￥2500.0 |
| 规格： | 25 mg | 产品价格： | ￥5000.0 |
Acetyl Coenzyme A trisodium
产品活性：Acetyl-coenzyme A (Acetyl-CoA) trisodium 是一种膜非渗透性的中枢代谢中间体，参与 TCA 循环和氧化磷酸化代谢过程。Acetyl-coenzyme A trisodium 通过向目标氨基酸残基提供 (唯一供体) 乙酰基团，来完成蛋白质的翻译后乙酰化反应，从而调节各种细胞机制。Acetyl Coenzyme A trisodium 也是脂质合成的关键前体。
产品来源： www.medchemexpress.cn/acetyl-coenzyme-a-trisodium.html
研究领域：Others | Metabolic Enzyme/Protease | Autophagy
作用靶点：Oxidative Phosphorylation | Endogenous Metabolite | Autophagy结构分类：其他类 | 结构分类
In Vitro: Acetyl coenzyme A trisodium increases cytoplasmic protein acetylation in starved U2OS cells while reducing starvation-induced autophagic fluxes. (U2OS cells stably expressing GFP-LC3 and are microinjected with Acetyl coenzyme A trisodium; incubated in nutrient-free conditions in the presence of 100 nM BafA1 and fixed after 3 h).
In Vivo: Acetyl coenzyme A trisodium blunts pressure overload-induced cardiomyopathy in a mice cardiac pressure overload model by Suppressing maladaptive autophagy.?Mice deprived of food (but with access to water ad libitum) for 24 h exhibit a significant reduction in total Acetyl coenzyme A trisodium levels in several organs, including the heart and muscles, corresponding to a decrease in protein acetylation levels. However, the same experimental conditions have no major effects on Acetyl coenzyme A trisodium concentrations in the brain and actually increase hepatic Acetyl coenzyme A trisodium and protein acetylation levels.
相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Metabolism/Protease Compound Library | Natural Product Library | Autophagy Compound Library | Human Endogenous Metabolite Compound Library | Nucleotide Compound Library | Mitochondria-Targeted Compound Library | Glucose Metabolism Compound Library | Food-Sourced Compound Library | Human Metabolite Library | Heterocyclic Compound Library | TCA Cycle Compound Library | Animal-Sourced Natural Product Library | Cell Death Library | Rapamycin | 3-Methyladenine | Acetylcysteine | 5-Fluorouracil | ATP | Retinoic acid | Hydrocortisone | CCCP | Estradiol | Nicotinamide | Prostaglandin E2 | AICAR | Docetaxel | Palmitic acid | Isoprenaline hydrochloride | FCCP | L-Ascorbic acid | Cytarabine | Melatonin | Oligomycin | Calcitriol | Valproic acid | Capsaicin | Arachidonic acid | Oleic acid | β-Nicotinamide mononucleotide | Acetaminophen | Biotin | Corticosterone | NAD+
产品活性：Acetyl-coenzyme A (Acetyl-CoA) trisodium 是一种膜非渗透性的中枢代谢中间体，参与 TCA 循环和氧化磷酸化代谢过程。Acetyl-coenzyme A trisodium 通过向目标氨基酸残基提供 (唯一供体) 乙酰基团，来完成蛋白质的翻译后乙酰化反应，从而调节各种细胞机制。Acetyl Coenzyme A trisodium 也是脂质合成的关键前体。
产品来源： www.medchemexpress.cn/acetyl-coenzyme-a-trisodium.html
研究领域：Others | Metabolic Enzyme/Protease | Autophagy
作用靶点：Oxidative Phosphorylation | Endogenous Metabolite | Autophagy结构分类：其他类 | 结构分类
In Vitro: Acetyl coenzyme A trisodium increases cytoplasmic protein acetylation in starved U2OS cells while reducing starvation-induced autophagic fluxes. (U2OS cells stably expressing GFP-LC3 and are microinjected with Acetyl coenzyme A trisodium; incubated in nutrient-free conditions in the presence of 100 nM BafA1 and fixed after 3 h).
In Vivo: Acetyl coenzyme A trisodium blunts pressure overload-induced cardiomyopathy in a mice cardiac pressure overload model by Suppressing maladaptive autophagy.?Mice deprived of food (but with access to water ad libitum) for 24 h exhibit a significant reduction in total Acetyl coenzyme A trisodium levels in several organs, including the heart and muscles, corresponding to a decrease in protein acetylation levels. However, the same experimental conditions have no major effects on Acetyl coenzyme A trisodium concentrations in the brain and actually increase hepatic Acetyl coenzyme A trisodium and protein acetylation levels.
相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Metabolism/Protease Compound Library | Natural Product Library | Autophagy Compound Library | Human Endogenous Metabolite Compound Library | Nucleotide Compound Library | Mitochondria-Targeted Compound Library | Glucose Metabolism Compound Library | Food-Sourced Compound Library | Human Metabolite Library | Heterocyclic Compound Library | TCA Cycle Compound Library | Animal-Sourced Natural Product Library | Cell Death Library | Rapamycin | 3-Methyladenine | Acetylcysteine | 5-Fluorouracil | ATP | Retinoic acid | Hydrocortisone | CCCP | Estradiol | Nicotinamide | Prostaglandin E2 | AICAR | Docetaxel | Palmitic acid | Isoprenaline hydrochloride | FCCP | L-Ascorbic acid | Cytarabine | Melatonin | Oligomycin | Calcitriol | Valproic acid | Capsaicin | Arachidonic acid | Oleic acid | β-Nicotinamide mononucleotide | Acetaminophen | Biotin | Corticosterone | NAD+
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Acetyl Coenzyme A trisodium乙酰辅酶A钠盐,102029-73-2
￥545 - 5000
