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文献和实验实验原理 The Dynabeads SILANE genomic DNA kit provides an excellent tool for isolation of genomic DNA from human blood, following a simple separation protocol. A buffer is first added to the sample for lysis, followed
Comparative Genomic Hybridization(CGH)
. For an example of how this technique has been utilized by the NCI Prostate Cancer Working Group see the section on Cell Lines. DNA RNAProteomic DNA sequence copy number changes throughout the genome in a single hybridization. CGH is based
cell lung carcinoma (SCLC), squamous cell carcinoma, and adenocarcinoma, are all thought to arise from bronchoepithelial cells (2 ). Normal human cells are not easily coerced into becoming cancerous as numerous mutations are necessary to subvert
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