Broadpharm代理商-HEX phosphoramid

An Aminooxy‐Functionalized Non‐Nucleosidic Phosphoramidite for the Construction of Multiantennary Oligonucleotide Glycoconjugates on a Solid Support

, a method is described that allows construction of multiantennary oligonucleotide glycoconjugates on a solid support. A bis(hydroxymethyl)malondiamide?based phosphoramidite that contains two phthaloyl?protected aminooxy groups compatible with normal chain

Synthesis of Building Blocks and Oligonucleotides with {G}O6‐Alkyl‐O6{G} Cross‐Links

? or a mono?phosphoramidite synthesis strategy can be employed. Both procedures require the preparation of a protected 2??deoxyguanosine?containing dimer where the two nucleosides are attached at the O6 ?atoms by an alkyl linker. This linker is introduced

Modification of the 5′ Terminus of Oligodeoxyribonucleotides for Conjugation with Ligands

for phosphoramidite? or H?phosphonate?mediated oligonucleotide synthesis.         GO TO THE FULL PROTOCOL: PDF or HTML at Wiley Online Library