重组人骨形态发生蛋白5，His-标签（无动物源）（BMP-5

重组人骨形态发生蛋白5（BMP-5）[PRP1198] - 高纯度无动物源细胞因子

产品概述

本产品为大肠杆菌表达的动物源游离重组蛋白，通过SDS-PAGE验证纯度>98%，适用于细胞培养相关研究。其生物活性经ATDC5细胞碱性磷酸酶诱导实验验证（ED₅₀ <0.17 μg/mL）。

关键参数

• 分子特性：138氨基酸（Ala317-His454）｜16.57 kDa｜His标签
• 质量控制：LAL法检测内毒素<0.1 EU/μg
• 蛋白稳定性：预装20mM柠檬酸钠+0.2M NaCl缓冲体系（pH3.5）
• 功能验证：TGF-β受体结合｜SMAD信号激活｜软骨合成调控

产品规格与价格

规格	价格（RMB）	货期
5 μg	588	现货
20 μg	1,498	现货
100 μg	5,998	咨询
1 mg	定制生产（详询客服）

保存与运输

• 储存条件：-20℃冻存（冻干粉有效期12个月）
• 复溶建议：≥100 μg/mL浓度复溶｜配套缓冲液优先
• 运输方式：蓝冰冷链运输（维持2-8℃）

使用须知

• 使用前需离心处理冻干粉
• 稀释建议添加载体蛋白（0.1% BSA/10% FBS/5%海藻糖）
• 复溶后分装冻存避免反复冻融（≤3次）

重要声明

本产品仅限研究使用，不适用于临床诊断或人体应用。具体应用场景请自行确认专利合规性。

技术背景

BMP-5（Gene ID:653｜UniProt:P22003）属于TGF-β超家族，通过调控醛固酮生物合成和上皮间质转化等过程，在软骨发育中起关键作用。

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注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

Recombinant Human Bone Morphogenetic Protein 5 (BMP-5) [PRP1198] - High Purity Animal-Free Cytokine

Product Overview

This product is an E. coli-expressed animal-free recombinant protein, verified by SDS-PAGE with >98% purity, suitable for cell culture-related research. Its bioactivity has been validated by alkaline phosphatase induction assay in ATDC5 cells (ED₅₀ <0.17 μg/mL).

Key Parameters

• Molecular Characteristics: 138 amino acids (Ala317-His454)｜16.57 kDa｜His-tag
• Quality Control: Endotoxin <0.1 EU/μg by LAL assay
• Protein Stability: Pre-formulated in 20mM sodium citrate + 0.2M NaCl buffer (pH3.5)
• Functional Validation: TGF-β receptor binding｜SMAD signaling activation｜Cartilage synthesis regulation

Specifications & Pricing

Specification	Price (RMB)	Lead Time
5 μg	588	In stock
20 μg	1,498	In stock
100 μg	5,998	Inquire
1 mg	Custom production (contact sales)

Storage & Shipping

• Storage Conditions: -20℃ frozen (lyophilized powder stable for 12 months)
• Reconstitution Recommendation: ≥100 μg/mL concentration｜Preferential use with provided buffer
• Shipping Method: Blue ice cold chain transport (maintained at 2-8℃)

Usage Notes

• Centrifuge lyophilized powder before use
• Recommended to add carrier proteins for dilution (0.1% BSA/10% FBS/5% trehalose)
• Avoid repeated freeze-thaw cycles after reconstitution (≤3 times)

Important Notice

This product is for research use only, not for clinical diagnosis or human applications. Users must verify patent compliance for specific applications.

Technical Background

BMP-5 (Gene ID:653｜UniProt:P22003) belongs to the TGF-β superfamily and plays a crucial role in cartilage development by regulating aldosterone biosynthesis and epithelial-mesenchymal transition processes.

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Note: The above information may be subject to changes due to product optimization and upgrades. Please contact Yakonin for the latest details.