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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
武汉天德
- 库存:
88
- 靶点:
详询
- 级别:
科研级
- 目录编号:
TD-230052
- 克隆性:
单克隆
- 抗原来源:
peptiede
- 保质期:
1年
- 抗体英文名:
beta Amyloid 1-42 Mouse mAb
- 抗体名:
Anti-beta Amyloid 1-42)
- 标记物:
详询
- 宿主:
Mouse
- 适应物种:
Human
- 免疫原:
Human beta Amyloid peptide
- 亚型:
lgG
- 形态:
Liquit
- 应用范围:
WB,ELISA
- 保存条件:
-20℃
- 浓度:
1mg/ml
- 规格:
50μl/100μl
| 规格: | 50μl | 产品价格: | 询价 |
|---|---|---|---|
| 规格: | 100μl | 产品价格: | 询价 |
货号:TD-230052
- Product Name
beta Amyloid 1-42 Mouse mAb - Gene Name
A4 - Alternative Names
Abeta42,Amyloid-beta protein 42,Beta amyloid protein 42,Beta APP42, - SwissProt ID
P05067 - Gene ID
351 - Background
Amyloid-beta peptides are lipophilic metal chelators with metal-reducing activity. Bind transient metals such as copper, zinc and iron. In vitro, can reduce Cu2+ and Fe3+ to Cu+ and Fe2+, respectively. Amyloid-beta protein 42 is a more effective reductant than amyloid-beta protein 40. Amyloid-beta peptides bind to lipoproteins and apolipoproteins E and J in the CSF and to HDL particles in plasma, inhibiting metal-catalyzed oxidation of lipoproteins. APP42-beta may activate mononuclear phagocytes in the brain and elicit inflammatory responses. Promotes both tau aggregation and TPK II-mediated phosphorylation. Interaction with overexpressed HADH2 leads to oxidative stress and neurotoxicity. Also binds GPC1 in lipid rafts. - Research Field
Neuroscience - Product Categories
Primary antibody - Host
Mouse - Reactivity
Human - Application
WB,ELISA - Dilution Ratio
WB: 1/500-1/1000 ELISA: 1/1000 - Molecular Weight
Calculated MW: 4.4 kDa; Obs/erved MW: 90-130 kDa crosslinked with BSA - Clonality
Monoclonal Antibody - Clonality No.
16D13 - Isotype
IgG2b - Immunogen
Human beta Amyloid peptide - Purification
Affinity Purified - Conjugation
Unconjugated - Modification
Unmodified - Form
Liquid - Buffer System
Liquid in PBS containing 0.09% sodium azide as a preservative. - Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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