- 询价
- Tanda
- 中国
- TD-230052
- 2025年09月25日
- WB,ELISA
- Mouse
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Human beta Amyloid peptide
- 亚型：
lgG
- 形态：
Liquit
- 保存条件：
-20℃
- 克隆性：
单克隆
- 标记物：
详询
- 适应物种：
Human
- 抗原来源：
peptiede
- 目录编号：
TD-230052
- 级别：
科研级
- 库存：
88
- 供应商：
武汉天德
- 宿主：
Mouse
- 应用范围：
WB,ELISA
- 浓度：
1mg/ml
- 靶点：
详询
- 抗体英文名：
beta Amyloid 1-42 Mouse mAb
- 抗体名：
Anti-beta Amyloid 1-42）
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | 询价 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | 询价 |
货号：TD-230052
- Product Name
beta Amyloid 1-42 Mouse mAb - Gene Name
A4 - Alternative Names
Abeta42，Amyloid-beta protein 42，Beta amyloid protein 42，Beta APP42， - SwissProt ID
P05067 - Gene ID
351 - Background
Amyloid-beta peptides are lipophilic metal chelators with metal-reducing activity. Bind transient metals such as copper, zinc and iron. In vitro, can reduce Cu2+ and Fe3+ to Cu+ and Fe2+, respectively. Amyloid-beta protein 42 is a more effective reductant than amyloid-beta protein 40. Amyloid-beta peptides bind to lipoproteins and apolipoproteins E and J in the CSF and to HDL particles in plasma, inhibiting metal-catalyzed oxidation of lipoproteins. APP42-beta may activate mononuclear phagocytes in the brain and elicit inflammatory responses. Promotes both tau aggregation and TPK II-mediated phosphorylation. Interaction with overexpressed HADH2 leads to oxidative stress and neurotoxicity. Also binds GPC1 in lipid rafts. - Research Field
Neuroscience - Product Categories
Primary antibody - Host
Mouse - Reactivity
Human - Application
WB,ELISA - Dilution Ratio
WB: 1/500-1/1000 ELISA: 1/1000 - Molecular Weight
Calculated MW: 4.4 kDa; Obs/erved MW: 90-130 kDa crosslinked with BSA - Clonality
Monoclonal Antibody - Clonality No.
16D13 - Isotype
IgG2b - Immunogen
Human beta Amyloid peptide - Purification
Affinity Purified - Conjugation
Unconjugated - Modification
Unmodified - Form
Liquid - Buffer System
Liquid in PBS containing 0.09% sodium azide as a preservative. - Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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文献和实验该产品被引用文献
应用缩写
WB:蛋白质印迹法 IHC-P:石蜡切片样本的免疫组织化学法 IHC-F:冰冻切片样本的免疫组织化学法 ICC/IF:免疫细胞荧光 IP:免疫沉淀法 FC:流式细胞术 ChIP:染色质免疫沉淀法 ELISA:酶联免疫吸附测定
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文献支持
Anti-beta Amyloid 1-42）
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