- ￥800 - 2500
- Bioss
- bsm-60010R
- 2025年10月24日
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50ul/100ul/25ul
| 规格： | 50ul | 产品价格： | ￥1400.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2500.0 |
| 规格： | 25ul | 产品价格： | ￥800.0 |
| 产品编号 | bsm-60010R |
| 英文名称 | Insulin Recombinant Rabbit mAb |
| 中文名称 | 胰岛素重组兔单抗 |
| 英文别名 | ILPR; INS; Insulin A chain; Insulin B chain; IRDN; Proinsulin; Proinsulin precursor; IDDM2; INS_HUMAN; MODY10. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse, Rat |
| 抗体来源 | Rabbit |
| 免疫原 | A synthesized peptide derived from human Insulin |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Recombinant |
| 理论分子量 | 12 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 |
Cardiovascular > Atherosclerosis > Diabetes associated Metabolism > Types of disease > Diabetes Metabolism > Types of disease > Heart disease Metabolism > Types of disease > Obesity Neuroscience > Neurology process > Metabolism Signal Transduction > Growth Factors/Hormones > Insulin / Insulin-like |
| 亚基 | Heterodimer of a B chain and an A chain linked by two disulfide bonds. |
| 亚细胞定位 | Secreted. |
| 相似性 | Belongs to the insulin family. |
| 功能 | Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
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文献和实验[IF={{ 5.6 }}] {Zhongyi Xu. et al. A cucurbit[7]uril-mediated crosslinking-amplified microchannel resistance immunoassay via magnetic interception for point of care testing of insulin. TALANTA. 2025 Nov;294:128211} {} {Human}
[IF={{ 3.5 }}] {Anna Nakamura. et al. Zinc deficiency affects insulin secretion and alters insulin-regulated metabolic signaling in rats. J TRACE ELEM MED BIO. 2023 Dec;:127375} {IHC} {Rat}
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