Sample:
Lane 1: Mouse Embryo tissue lysates
Lane 2: Mouse Testis tissue lysates
Lane 3: Mouse Cerebrum tissue lysates
Lane 4: Rat Testis tissue lysates
Lane 5: Rat Cerebrum tissue lysates
Primary: Anti-Osterix (bs-25532R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 45 kDa
Observed band size: 50,58 kDa
- ￥1180 - 2800
- Bioss
- bs-25532R
- 2025年10月24日
- 产品信息以Bioss网站为准
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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-25532R |
| 英文名称 | Osterix Rabbit pAb |
| 中文名称 | 成骨相关转录因子抗体 |
| 英文别名 | SP7_HUMAN; Transcription factor Sp7; OSX; Zinc finger protein osterix; Sp7 transcription factor; Osterix; |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse, Rat (Human, Cow) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from mouse Osterix |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 45 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Developmental Biology > Organogenesis > Skeletal development > Bone Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families Epigenetics and Nuclear Signaling > Transcription > Transcription Factors Stem Cells > Mesenchymal Stem Cells > Intracellular Stem Cells > Mesenchymal Stem Cells > Osteogenesis |
| 亚基 | Interacts with NO66; the interaction is direct and inhibits transcription activator activity. |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Osteoblast/chondrocyte specific. |
| 相似性 | Belongs to the Sp1 C2H2-type zinc-finger protein family. Contains 3 C2H2-type zinc fingers. |
| 功能 | Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences (By similarity). |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.[provided by RefSeq, Jul 2010] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验该产品被引用文献
[IF={{ 6.8 }}] {Jingxi Xu. et al. Titanium dioxide nanoparticles oral exposure induce osteoblast apoptosis, inhibit osteogenic ability and increase lipogenesis in mouse. ECOTOX ENVIRON SAFE. 2024 Jun;277:116367} {WB,ICC,IF} {Mouse}
[IF={{ 4.8 }}] {Guijiang Huang. et al. Osteoking inhibits apoptosis of BMSCs in osteoporotic rats via PI3K/AKT signaling pathway. J ETHNOPHARMACOL. 2024 Dec;:118961} {WB} {Rat}
[IF={{ 16.6 }}] {Shao Xi. et al. Rescuing SERCA2 pump deficiency improves bone mechano-responsiveness in type 2 diabetes by shaping osteocyte calcium dynamics. NAT COMMUN. 2024 Jan;15(1):1-22} {WB} {Mouse}
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Osterix Rabbit pAb(bs-25532R)-50ul/100ul/200ul
￥1180 - 2800
