- ￥1053 - 5265
- Biorbyt
- 英国
- orb1943496
- 2026年08月07日
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- 技术资料
- 保存条件：
详询
- 保质期：
12 months from date of receipt.
- 英文名：
RIPK1-IN-17
- 库存：
99
- 供应商：
Biorbyt
- CAS号：
3033385-59-7
- 规格：
1 mg/5 mg/10 mg/25 mg/50 mg
| 规格： | 1 mg | 产品价格： | ￥1053.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥1755.0 |
| 规格： | 10 mg | 产品价格： | ￥2457.0 |
| 规格： | 25 mg | 产品价格： | ￥3744.0 |
| 规格： | 50 mg | 产品价格： | ￥5265.0 |
类别: Small Molecules
描述: RIPK1-IN-17 is a dual RIPK1/RIPK3 inhibitor that blocks necroptosis by preventing the phosphorylation of RIPK1, RIPK3, and MLKL. It has demonstrated in vivo efficacy by protecting mice from TNF-induced systemic inflammatory response syndrome (SIRS), hypothermia, and lethality, making it a valuable research tool for studying necroptosis in inflammatory disease models.
别名: RIP kinase, RIPkinase
靶点: RIP kinase
分子式: C26H19F4N3O3S
分子量: 529.51
纯度: 95.22% (May vary between batches)
SMILES: FC1=C(NC(CC2=CC=CC(OC(F)(F)F)=C2)=O)C=C(C3=CC=C(N=C(NC(C4CC4)=O)S5)C5=C3)C=C1
溶解度: DMSO:40 mg/mL (75.54 mM)
研究领域: Cell Biology, Signal Transduction
保存条件: -20°C
备注: For research use only.
描述: RIPK1-IN-17 is a dual RIPK1/RIPK3 inhibitor that blocks necroptosis by preventing the phosphorylation of RIPK1, RIPK3, and MLKL. It has demonstrated in vivo efficacy by protecting mice from TNF-induced systemic inflammatory response syndrome (SIRS), hypothermia, and lethality, making it a valuable research tool for studying necroptosis in inflammatory disease models.
别名: RIP kinase, RIPkinase
靶点: RIP kinase
分子式: C26H19F4N3O3S
分子量: 529.51
纯度: 95.22% (May vary between batches)
SMILES: FC1=C(NC(CC2=CC=CC(OC(F)(F)F)=C2)=O)C=C(C3=CC=C(N=C(NC(C4CC4)=O)S5)C5=C3)C=C1
溶解度: DMSO:40 mg/mL (75.54 mM)
研究领域: Cell Biology, Signal Transduction
保存条件: -20°C
备注: For research use only.
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RIPK1-IN-17，orb1943496，Biorbyt
￥1053 - 5265
