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- 文献和实验
- 技术资料
- 保存条件:
详询
- 保质期:
12 months from date of receipt.
- 英文名:
MSA-2 dimer
- 库存:
99
- 供应商:
Biorbyt
- CAS号:
2377881-92-8
- 规格:
25 mg
描述: MSA-2 is an orally bioavailable, non-nucleotide STING agonist that binds as a dimer with a Kd of 145 µM. It exhibits superior cell permeability over cyclic dinucleotides and demonstrates durable antitumor and immunogenic activity in preclinical in vivo studies, making it a valuable research tool for immuno-oncology.
靶点: STING,Others
分子式: C29H28O8S2
分子量: 568.66
SMILES: COc1cc2sc(cc2cc1CCCc1cc2cc(sc2cc1OC)C(=O)CCC(O)=O)C(=O)CCC(O)=O
研究领域: Immunology & Inflammation
保存条件: -20°C
备注: For research use only.
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文献和实验Combination Lesion Models of MSA
Multiple system atrophy (MSA) is a rapidly progressive neurodegenerative disorder presenting with parkinsonism, cerebellar ataxia, and autonomic failure in various combinations. The main pathological hallmark is the formation of (oligo
警惕!披着 “帕金森疾病”外衣的罕见病—多系统萎缩 多系统萎缩(MSA)是成年期发病、散发性的神经系统变性疾病,临床表现为不同程度的自主神经功能障碍、对左旋多巴类药物反应不良的帕金森综合征、小脑性共济失调和锥体束征等症状。 由于在起病时累及这三个系统的先后不同,所以造成的临床表现各不相同。但随着疾病的发展,最终出现这三个系统全部损害的病理表现和临床表现。 多系统萎缩病因 目前认为 MSA 的发病机制可能有两条途径: 1.原发性少突胶质细胞病变假说,即先出现以 α-突触核蛋白(α
Multiple Protein Sequence Alignment with MSAProbs
Multiple sequence alignment (MSA) generally constitutes the foundation of many bioinformatics studies involving functional, structural, and evolutionary relationship analysis between sequences. As a result of the exponential computational
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